Results 131 to 140 of about 982,655 (280)

An FPGA-oriented fully parallel algorithm for multiplying dual quaternions [PDF]

, 2015
This paper presents a low multiplicative complexity fully parallel algorithm for multiplying two dual quaternions. The “pen-and-paper” multiplication of two dual quaternions requires 64 real multiplications and 56 real additions. More effective solutions
Cariow, A., Cariowa, G., Witczak, M.
core  

A Dual-Quaternion Framework for Bennett-Limit Diagnostics in Rigid Kresling Origami FOLD–TWIST–FOLD Robots

Mathematics
This paper presents a dual-quaternion (DQ) framework for the rigid-kinematic modeling and validation of rigid hexagonal Kresling origami robots executing a prescribed FOLD–TWIST–FOLD motion. Triangular panels are modeled as rigid bodies, and crease lines
Bogdan Fustei, Monica Leba, Andreea Ionica   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

A NOTE ON RELATION BETWEEN POINT-LINE DISPLACEMENT AND EQUIFORM TRANSFORMATION

Journal of New Theory, 2015
− The present paper studies the relation between the point-line displacement and theequiform transformation in Euclidean 3-space R3. A point-line can be transformed into another pointline via an equiform transformation.
Esra B. Koç Öztürk, Ufuk Öztürk, Yusuf Yaylı   +2 more
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Implementation of the dual quaternion algorithm for 3D similarity-based coordinate transformation between Ghana’s local geodetic datum and WGS84

Reports on Geodesy and Geoinformatics
Modern surveying practice has embraced the use of Global Navigation Satellite System (GNSS) technology due to its attainable precision and uncomplicated functionality.
Ziggah Yao Yevenyo, Mantey Saviour, Laari Prosper Basommi   +2 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Dual Quaternions Robotics: A) The 3R Planar Manipulator [PDF]

, 2018
Kinematics analysis studies the relative motions, such as, first of all, the displacement in space of the end effector of a given robot, and thus its velocity and acceleration, associated with the links of the given robot that is usually designed so that
Dahou, Mohammed Ben-Ahmed-; Algeria Structural Mechanics Research Laboratory, Mechanical Engineering Department, Blida University, Gouasmi, Belkacem; Algeria Structural Mechanics Research Laboratory, Mechanical Engineering Department, Blida University, Gouasmi, Mahmoud; Algeria Structural Mechanics Research Laboratory, Mechanical Engineering Department, Blida University   +2 more
core