Results 111 to 120 of about 92,974 (284)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Contribution of social activity participation to the relationship between sensory impairment, physical performance and cognitive decline: a longitudinal study in China

Frontiers in Aging Neuroscience
ObjectivesThis study examined the impact of sensory impairment (hearing and/or vision) combined with poor physical performance on cognitive decline and assessed whether social activity participation mediated this relationship.MethodsMultilevel models ...
Lei Lei, Lei Lei, Yinuo Zhou, Lizhen Ye, Yanfang Yang   +4 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Computational neurorehabilitation: modeling plasticity and learning to predict recovery [PDF]

, 2016
Despite progress in using computational approaches to inform medicine and neuroscience in the last 30 years, there have been few attempts to model the mechanisms underlying sensorimotor rehabilitation.
Burdet, E, Casadio, M, Krakauer, JW, Kwakkel, G, Lang, CE, Reinkensmeyer, DJ, Schweighofer, N, Swinnen, SP, Ward, NS   +8 more
core   +5 more sources

Feeling vibrations from a hearing and dual-sensory impaired perspective

Music and Medicine, 2017
Working with hearing and dual-sensory impaired clients presents challenges for music therapy professionals. Feeling and experiencing the vibrations produced by music help to understand what the concept of music is. Music and vibroacoustic therapies have overlapping effects.
Russ Palmer, Olav Skille, Riitta Lahtinen, Stina Ojala   +3 more
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Direct and generative retrieval of autobiographical memories : the roles of visual imagery and executive processes [PDF]

, 2017
Two experiments used a dual task methodology to investigate the role of visual imagery and executive resources in the retrieval of specific autobiographical memories.
Anderson, Rachel J., Dean, Graham M., Dewhurst, Stephen A.   +2 more
core   +3 more sources

Associations between sensory impairment and functional limitations among older Chinese adults: mediating roles of social isolation and cognition

BMC Geriatrics
Background The high prevalence of sensory impairment and functional limitations in older adults is a significant concern, yet there is limited understanding of the relationship between these two conditions.
Bo Xin, Yuxin He, Yixin Wu, Di Zhang, Jiaxin Liu, Shan Yang, Panpan Shi, Han Su, Wenhui Jiang   +8 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

School rules [PDF]

, 2008
Gordon Murray and Alan Dunlop Architects designed an extraordinary, internationally award-winning school that started with a most challenging set of constraints.
Murray, Gordon
core   +1 more source