Results 1 to 10 of about 158,041 (264)

Generation of a homozygous LRP2 knockout human embryonic stem cell line (FDCHDPe010-A-56) by CRISPR/Cas9 system

open access: yesStem Cell Research, 2021
LRP2 is mainly expressed in the cell membrane of epithelia, maintaining normal endocytosis of nutrients from the extracellular microenvironment and mediating growth factor signals. The deficiency of LRP2 can result in abnormal lysosomal and mitochondrial
Jie You   +3 more
doaj   +1 more source

Effects of perfluorooctane on the retina as a short-term and small amounts remnant in rabbits [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To investigate changes in the rabbit retina after short-term and small amounts tamponade of perfluorooctane (PFO). METHODS: New Zealand rabbits were used, and 48 eyes were randomly and evenly assigned into four different groups.
Qing-Chen Li   +5 more
doaj   +1 more source

Visual impairment in children with multiple disabilities in schools for children with special needs in South India

open access: yesIndian Journal of Ophthalmology, 2022
Purpose: To understand/assess ocular and functional vision impairment in children with multiple disabilities with a functional vision assessment battery in addition to standard ophthalmic examinations in an outreach setting.
SahithyaBhaskaran   +3 more
doaj   +1 more source

Childhood vision impairment [PDF]

open access: yesBritish Journal of Ophthalmology, 2004
Childhood blindness is ranked second only to cataract on the global burden of eye disease While the number of children with vision loss and blindness is relatively low in comparison with the number of older people with vision loss, the impact as measured in disability adjusted life years (DALY) ranks childhood blindness second only to cataract on the ...
openaire   +2 more sources

Retinal Vascular Autoregulation during Phase IV of the Valsalva Maneuver: An Optical Coherence Tomography Angiography Study in Healthy Chinese Adults

open access: yesFrontiers in Physiology, 2017
The impairment of retinal vascular autoregulation can be an early manifestation of many systemic and ocular diseases. Therefore, quantifying retinal vascular autoregulation in a non-invasive manner is very important. This study evaluated the effects of a
Yuan Zong   +14 more
doaj   +1 more source

Vision impairment in the Pacific region [PDF]

open access: yesBritish Journal of Ophthalmology, 2002
The Western Pacific region is one of great diversity, containing the most populous country, China, and many small Pacific island countries. This review describes the prevalence of blindness and vision loss, illustrates the changing trends in the important causes of vision loss and blindness, and the stages of development of the delivery of eye care ...
J E, Keeffe, K, Konyama, H R, Taylor
openaire   +2 more sources

Rifle Shooting for Athletes With Vision Impairment: Does One Class Fit All?

open access: yesFrontiers in Psychology, 2019
Revised evidence-based classification criteria introduced for shooting for athletes with vision impairment (VI shooting) suggest that athletes with impaired contrast sensitivity (CS) and visual acuity (VA) should be eligible for inclusion in the sport ...
Peter M. Allen   +6 more
doaj   +1 more source

Fear of Falling in Vision Impairment [PDF]

open access: yesOptometry and Vision Science, 2015
ABSTRACT Falls are the leading cause of injury‐related morbidity and mortality among older adults. In addition to the resulting physical injury and potential disability after a fall, there are also important psychological consequences, including depression, anxiety, activity restriction, and fear of falling. Fear of falling affects 20
White, Ursula   +3 more
openaire   +3 more sources

Contrast Sensitivity Is a Significant Predictor of Performance in Rifle Shooting for Athletes With Vision Impairment

open access: yesFrontiers in Psychology, 2018
Purpose: In order to develop an evidence-based, sport-specific minimum impairment criteria (MIC) for the sport of vision-impaired (VI) shooting, this study aimed to determine the relative influence of losses in visual acuity (VA) and contrast sensitivity
Peter M. Allen   +7 more
doaj   +1 more source

Protective effects of blocking PD-1 pathway on retinal ganglion cells in a mouse model of chronic ocular hypertension

open access: yesFrontiers in Immunology, 2023
PurposeIn this study, we aimed to investigate whether Programmed cell death 1 ligand 1/programmed cell death 1 ligand 2 (PD-L1/PD-L2) double knockout (dKO) has a protective effect on RGCs in a mouse model of chronic ocular hypertension (COHT).MethodsWe ...
Siqi Sheng   +19 more
doaj   +1 more source

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