Results 121 to 130 of about 150,972 (303)
Frontiers in PsychologyObjectivesThrough a longitudinal study, we explored the relationship between sensory impairments and depression in the elderly, and examined the mediating roles of daily activity capability and social participation within this relationship.MethodsBased ...
Chunjie Huang, Xiaoqing He, Xin Zhang
doaj +1 more source
Emotional well-being in people with sight loss: Lessons from the grey literature [PDF]
, 2010 Literature that is not peer-reviewed and distributed through a publisher is known as ‘grey’. As it is used to inform policy and practice we reviewed the grey literature concerning emotional well-being in people with sight loss.
Gosney, M.A., Nyman, S.R., Victor, C.R.
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
BMC Public HealthBackground To date, the mechanisms underlying the relationship between sensory impairment and new-onset arthritis remain inadequately understood. This study aims to investigate the mediating role of depressive symptoms in the longitudinal association ...
Chenyang Li +6 more
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Frontiers in Aging NeuroscienceObjectivesThis study examined the impact of sensory impairment (hearing and/or vision) combined with poor physical performance on cognitive decline and assessed whether social activity participation mediated this relationship.MethodsMultilevel models ...
Lei Lei +4 more
doaj +1 more source
Defective neural motor speech mappings as a source for apraxia of speech : evidence from a quantitative neural model of speech processing [PDF]
, 2011 This unique resource reviews research evidence pertaining to best practice in the clinical assessment of established areas such as intelligibility and physiological functioning, as well as introducing recently developed topics such as conversational ...
Kroger, Bernd, Lowit, Anja, Miller, N.
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Using multimedia to enhance the accessibility of the learning environment for disabled students: reflections from the Skills for Access project [PDF]
, 2006 As educators' awareness of their responsibilities towards ensuring the accessibility of the learning environment to disabled students increases, significant debate surrounds the implications of accessibility requirements on educational multimedia.
Gregor, Peter +2 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Event-related brain potential correlates of human auditory sensory memory-trace formation [PDF]
, 2005 The event-related potential (ERP) component mismatch negativity (MMN) is a neural marker of human echoic memory. MMN is elicited by deviant sounds embedded in a stream of frequent standards, reflecting the deviation from an inferred memory trace of the ...
Baldeweg, T +4 more
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The effects of dividing attention on smooth pursuit eye tracking [PDF]
, 2005 No description ...
Hutton, Samuel, Tegally, Davinder
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