Results 91 to 100 of about 311,557 (292)

Higher-order thoughts in action : Consciousness as an unconscious re-description process [PDF]

, 2012
Peer ...
Antoine Pasquali, Axel Cleeremans, Baars B. J., Bert Timmermans, Dennett D. C., Dienes Z., Frith C. D., Hinton G. E., Hofstadter D. R., Karmiloff-Smith A., Leonhard Schilbach, Maniscalco B., Mealor A., Noë A., Noë A., Reddy V., Rosenthal D. M., Schilbach L., Sutton R. S.   +18 more
core   +1 more source

Prevalence, diagnoses and rehabilitation services related to severe dual sensory loss (DSL) in older persons: a cross-sectional study based on medical records

International Journal of Audiology, 2020
Objective To estimate the prevalence of severe dual sensory loss (DSL) among older persons (aged ≥65 years) in the Swedish population, to identify the diagnoses that cause severe DSL, and to identify rehabilitation services in which the participants have
Elin Lundin, Stephen E. Widén, Moa Wahlqvist, A. Anderzén-Carlsson, S. Granberg   +4 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Multidimensional relationships between sensory perception and cognitive aging

Frontiers in Aging Neuroscience
A growing literature suggests that declines in sensory/perceptual systems predate cognitive declines in aging, and furthermore, they are highly predictive for developing Alzheimer’s disease and Alzheimer’s related dementias (ADRD). While vision, hearing,
Lakshmi Kannan, Esteban Sebastian Lelo de Larrea-Mancera, Marcello Maniglia, Mariya M. Vodyanyk, Frederick J. Gallun, Susanne M. Jaeggi, Aaron R. Seitz, Aaron R. Seitz   +7 more
doaj   +1 more source

Third-Party Impact of Dual Sensory Loss on Neuropsychiatric Symptom-Related Distress among Friends and Family

Gerontology, 2020
Background: Vision loss and hearing loss are common in later life and are associated with cognitive impairment and neuropsychiatric symptoms. There is a need to better understand how individual characteristics, such as poor sensory functioning, are ...
K. Kiely, M. Mortby, K. Anstey
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Immune cognition, social justice and asthma: structured stress and the developing immune system [PDF]

, 2001
We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is conjoined with central nervous system cognition, and with the cognitive function of the ...
Fullilove, Mindy, Wallace, Deborah, Wallace, Rodrick   +2 more
core  

Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]

, 2017
Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo, Bharti, Komal, Bologna, Matteo, Giannã¬, Costanza, Pantano, Patrizia, Petsas, Nikolaos, Piattella, Maria Cristina, Suppa, Antonio, Tona, Francesca, Upadhyay, Neeraj   +9 more
core   +2 more sources

Effects of a Dual Sensory Loss Protocol on Hearing Aid Outcomes

Ear & Hearing, 2015
Dual sensory loss (DSL; concurrent vision and hearing loss) negatively affects quality of life. As speechreading is hampered, use of hearing aids (HAs) is important for older adults with DSL. However, due to vision loss, use of small and complex HAs is assumed to be difficult.
Vreeken, H.L., van Rens, G.H.M.B., Kramer, S.E., Knol, D.L., van Nispen, R.M.A.   +4 more
openaire   +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source