Results 71 to 80 of about 198,562 (263)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scandinavian Journal of Disability Research, 2016 Deafblindness is a rare condition with multiple causes. Given its rarity, professionals generally have limited knowledge of this condition and insufficient experience managing it.
Agneta Anderzén-Carlsson
doaj +1 more source
Underwater Image Enhancement Based on Generative Adversarial Networks
Shanghai Jiaotong Daxue xuebao, 2022 This paper proposes an underwater image correction and enhancement algorithm based on generative adversarial networks. In this algorithm, the multi-scale kernel is applied to the improved residual module to construct a generator, which realizes the ...
LI Yu, YANG Daoyong, LIU Lingya, WANG Yiyin
doaj +1 more source
Immune cognition, social justice and asthma: structured stress and the developing immune system [PDF]
, 2001 We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is conjoined with central nervous system cognition, and with the cognitive function of the ...
Fullilove, Mindy +2 more
core
Cross-modal extinction in a boy with severely autistic behaviour and high verbal intelligence [PDF]
, 2008 Anecdotal reports from individuals with autism suggest a loss of awareness to stimuli from one modality in the presence of stimuli from another. Here we document such a case in a detailed study of T.M., a 13-year-old boy with autism in whom significant ...
Adini, Y +10 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Reliability of Standardized Assessment for Adults who are Deafblind [PDF]
, 2011 This study assessed the reliability of the interRAI Community Health Assessment (interRAI CHA) and Deafblind Supplement (DbS). The interRAI CHA and DbS represents a multidimensional, standardized assessment instrument for use with adults (18 and older ...
Ashworth, Melody +8 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Prevalence of dual sensory impairment in veterans: a rapid systematic review
Frontiers in Rehabilitation SciencesDual sensory impairment (DSI) is prevalent in the older population, but due to exposure to military-related risk factors, it is a particular problem for veterans, older and younger.
Zara Raza +4 more
doaj +1 more source
JMIR Research Protocols, 2021 BackgroundAge-related vision impairments and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (eg, macular degeneration/glaucoma and Alzheimer’s disease ...
Wittich, Walter +8 more
doaj +1 more source