Results 91 to 100 of about 4,615,733 (305)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Numerical Solution of Soap Film Dual Problems

open access: yesExperimental Mathematics, 1995
The soap film problem is to minimize area, and its dual is to maximize the flux of a divergenceless bounded vector field. This paper discretizes the continuous problem and solves it numerically. This gives upper and lower bounds on the area of the globally minimizing film. In favorable cases, the method can be used to discover previously unknown films.
openaire   +3 more sources

Taguchi–grey relational analysis and response surface methodology for heat transfer optimization in tri-hybrid nanofluid flow with slip and heat source/sink effects

open access: yesFrontiers in Physics
A permeable shrinking sheet is a surface with time-dependent permeability and the sheet shrinks with time. In this study, the slip and heat sink/source effects are considered as an integrated medium which can model trihybrid nanofluids (THNFs) in a ...
Khaled Matarneh   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

New Solutions to Delsarte’s Dual Linear Programs

open access: yesIEEE Transactions on Information Theory
Understanding the maximum size of a code with a given minimum distance is a major question in computer science and discrete mathematics. The most fruitful approach for finding asymptotic bounds on such codes is by using Delsarte's theory of association schemes.
André Chailloux, Thomas Debris-Alazard
openaire   +4 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Dual solutions in MHD boundary layer flow of Carreau fluidover a shrinking sheet with convective boundary condition [PDF]

open access: yes, 2019
This paper studies on two-dimensional magnetohdrodynamics (MHD) boundary layer flow of Carreau fluid towards a non-linear shrinking sheet with convective boundary condition and non-linear thermal radiation.
Mohamed Isa, Siti Suzilliana Putri   +2 more
core   +1 more source

Existence of Nontrivial Solutions and High Energy Solutions for a Class of Quasilinear Schrödinger Equations via the Dual-Perturbation Method [PDF]

open access: yes, 2013
We study the quasilinear Schrödinger equation of the form , . Under appropriate assumptions on and , existence results of nontrivial solutions and high energy solutions are obtained by the dual-perturbation ...
Yu Chen, Xian Wu
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Transpiration effects on hybrid nanofluid flow and heat transfer over a stretching/shrinking sheet with uniform shear flow

open access: yesAlexandria Engineering Journal, 2020
This paper considers the effect of transpiration on hybrid nanofluid flow and heat transfer over a stretching/shrinking sheet for uniform shear flow. The similarity equations are attained from the governing equations by using similarity transformation ...
Iskandar Waini, Anuar Ishak, Ioan Pop
doaj   +1 more source

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