Results 91 to 100 of about 16,914,292 (257)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Work, Inequality, and the Dual Career Household [PDF]

open access: yes
Dual career households have the potential to be the most egalitarian of all households. However, while paid work is increasingly distributed evenly between career men and women, household time remains a social constraint for many women.
Dan Wheatley and Zhongmin Wu
core  

USING-A-DUAL-XPA2100-300-WATT-SIGNAL-AMP-FOR-ELECTROACOUSTIC-PROPULSION-RESEARCH

open access: yes, 2018
This repository contains data related to the use of a DUAL XPA2100 Audio Amplifier for use in electroacoustic propulsion ...
Cory Andrew Hofstad (5368814)
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Mapping of dual-use related intangible technology transfers in EUP2P partner countries and other third countries through "TIM Dual-Use"

open access: yes, 2022
Mapping of Dual-Use related ITTs in EUP2P partner countries and other third countries through “TIM Dual ...
Guest, Clara   +2 more
core  

Daily and Nondaily E‐Cigarette Use in Relation to Cigarette Consumption Among Current Smokers

open access: yesThe Clinical Respiratory Journal
Background Dual use of e‐cigarettes and conventional cigarettes is the most common pattern of e‐cigarette use among adults who smoke. A central unresolved question is whether e‐cigarettes partially displace cigarette consumption among dual users or ...
Yusuff Adebayo Adebisi
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Setting the publication of ‘dual-use research’ under the export authorisation process: the H5N1 case [PDF]

open access: yes, 2015
The main purpose of this article is to explore whether trade controls as currently implemented by national authorities in Europe and the US represent a suitable means for monitoring research of dual-use concern.
CHARATSIS Christos, Charatsis, Christos
core   +1 more source

Understanding dual financial participation in Uganda: a multivariate analysis of formal and informal financial inclusion

open access: yesCogent Economics & Finance
Uganda’s financial landscape is distinctly dualistic with regulated financial mechanisms coexisting with pervasive community-based ones such as Village Savings and Loan Associations (VSLAs) and Rotating Savings and Credit Associations (ROSCAs).
Christopher Kanakulya   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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