Results 101 to 110 of about 16,914,292 (257)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
AIArtificial intelligence (AI) is rapidly transforming virology by strengthening pandemic preparedness, enhancing our molecular understanding of virus–host interactions, and accelerating the discovery and development of novel antiviral therapies.
Adam W. Whisnant, Lars Dölken
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The teaching of ethics and core values in chemistry education
Chemistry Teacher InternationalThis special issue is deciated to the teaching of ethics in chemistry education. In this editorial the articles in this special issue are introduced. A short explanation how they fit into this specific special issue is given.
Apotheker Jan
doaj +1 more source
Euchembioj ReviewsCRISPR-based genome editing has moved rapidly from a laboratory technique into a contested object of governance. In public health framings, CRISPR is presented as a platform for treating rare and severe genetic diseases, advancing diagnostics, and ...
Zehra Durmus
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Physician Dual Practice: Access Enhancement or Demand Inducement? [PDF]
In many developing countries, the majority of physicians employed in government clinics also have a private practice. We develop a simple model to show that allowing dual practice helps low-income governments retain skilled physicians to assure patient ...
Karen Eggleston, Anupa Bir
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Tobacco Prevention and CessationIntroduction Electronic cigarettes (ECs) and heated tobacco products (HTPs) have gained popularity worldwide, despite concerns about their safety. In Italy, updated national data on these devices remain scarce.
Marco Scala +5 more
doaj +1 more source