Results 61 to 70 of about 16,914,292 (257)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Technikfolgenabschätzung in der ‚Zeitenwende‘: Ambivalenzen der Reflexion auf sicherheitsrelevante Technologien

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
Under the buzzword ‘Zeitenwende,’ new geopolitical requirements for national security and resilience are being negotiated, increasingly blurring the boundaries between civilian and military research.
Martina Philippi
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Associations between dual use of e-cigarettes and smoking cessation: a prospective study of smokers in England. [PDF]

open access: yes, 2019
BACKGROUND: It has been claimed that use of e-cigarettes in combination with cigarettes outside of a quit attempt ('dual use') reduces quitting among smokers.
Brown, Jamie   +11 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

A Dual Approach to Estimation With Constant Prices [PDF]

open access: yes
In a recent paper, Mundlak assumes that the price-taking, risk-neutral and profit-maximizing entrepreneur makes his decisions on the basis of a planning model that maximizes expected profit using expected prices.
Caputo, Michael R., Paris, Quirino
core  

Dual-Use Chemicals

open access: yes
Throughout history, chemical sciences have continuously advanced, generating a vast array of substances with significant industrial, medical and agricultural applications.
Matteo Guidotti   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Vape Smoking: Prevalence and Perception among Damnhour University Students [PDF]

open access: yesInternational Egyptian Journal of Nursing Sciences and Research
Background: E-cigarette or vape smoking is becoming a worldwide concern, yet vapinginformation is not widespread among Middle Eastern university students.
Naglaa Hussein
doaj   +1 more source

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