Results 71 to 80 of about 365,287 (261)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

DualCMNet: a lightweight dual-branch network for maize variety identification based on multi-modal feature fusion

open access: yesFrontiers in Plant Science
IntroductionThe accurate identification of maize varieties is of great significance to modern agricultural management and breeding programs. However, traditional maize seed classification methods mainly rely on single modal data, which limits the ...
Xinhua Bi   +8 more
doaj   +1 more source

A novel high yielding dual-purpose sorghum variety GDJ 1(Banas Surya) for semi-arid region of Gujarat

open access: yesElectronic Journal of Plant Breeding, 2021
The new sorghum variety GDJ 1 (Banas Surya) breed through pedigree selection method from the cross between SPV 2113 × GFS 5 at Sorghum Research Station, Sardarkrushinagar Dantiwada Agricultural University, Deesa, Gujarat.
R. A. Gami*, R. N. Patel, P. R. Patel and S. K. Jain
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Cohomological support loci for Abel-Prym curves

open access: yesLe Matematiche, 2008
For an Abel-Prym curve contained in a Prym variety, we determine the cohomological support loci of its twisted ideal sheaves and the dimension of its theta-dual.
Sebastian Casalaina Martin   +2 more
doaj  

Synergistic interactions in mixed-species biofilms of pathogenic bacteria from the respiratory tract

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2014
Introduction Mixed-species biofilms are involved in a wide variety of infections. We studied the synergistic interactions during dual-species biofilm formation among isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas ...
Maryam Varposhti   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Alfalfa and sorghum silages: Experiments indicate no difference between sweet forage-type sorghum and dual purpose-type when fed as silage to steers

open access: yesCalifornia Agriculture, 1959
Silage from a sweet forage sorghum with a low grain-to-stalk ratio–variety Rex–was compared to silage from a dual purpose forage sorghum with a higher grain-to-stalk ratio–variety Hegari– and both were compared to alfalfa hay and alfalfa silage in ...
J Meyer, G Lofgreen, N Ittner
doaj  

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