Results 31 to 40 of about 149,447 (303)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Defense of Belief-Credence Dualism [PDF]
, 2018 I defend belief-credence dualism, the view that we have both beliefs and credences and both attitudes are equally fundamental. First, I explain belief, credence, and three views on their relationship. Then, I argue for dualism.
Jackson, Elizabeth
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Discussing Medieval Dialogue between the Soul and the Body and Question of Dualism
Ars & Humanitas, 2015 This contribution is based on the rejection of medieval dualism or on distinguishing the body from the flesh, as suggested by Suzannah Biernoff (2002).
Barbara Peklar
doaj +1 more source
Formulating Consciousness: A Comparative Analysis of Searle’s and Dennett’s Theory of Consciousness [PDF]
, 2017 This research will argue about which theory of mind between Searle’s and Dennett’s can better explain human consciousness. Initially, distinctions between dualism and materialism will be discussed ranging from substance ...
Chua, John Moses
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
How Belief-Credence Dualism Explains Away Pragmatic Encroachment [PDF]
, 2019 Belief-credence dualism is the view that we have both beliefs and credences and neither attitude is reducible to the other. Pragmatic encroachment is the view that practical stakes can affect the epistemic rationality of states like knowledge or ...
Jackson, Elizabeth
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
DHARMAKIRTI, DAVIDSON, AND KNOWING REALITY [PDF]
, 2012 If we distinguish phenomenal effects from their noumenal causes, the former being our conceptual(ized) experiences, the latter their grounds or causes in reality as it is independent of our experience, then two contradictory positions with regards to ...
Brons, Lajos
core +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source