Results 41 to 50 of about 24,560 (302)
This Article identifies and theorizes a significant butpreviously overlooked feature of structuraldiscrimination: it frequently develops into two seeminglyopposing, yet in fact mutually supportive practices.
Swan, Sarah L.
core +5 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Holism, individualism, personalism: from Platonic dualism to the dispute over a source and status of human individuality (N. Elias, I. Berlin, R. Rorty) [PDF]
Individualism as a way of feeling and comprehension of reality has been a basic element of Western civilization for a long time. In 20th century individualism was criticized by personalism and similar currents.
Zbigniew Ambrożewicz
doaj
Lagged development and economic dualism
The work explores the hypothesis that today’s lagging economies, such as Italy, are not completely lacking in firms that are capable of achieving high levels of productivity, rather they simply do not have enough of them to absorb a sizeable portion of ...
G. FUÀ
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The growth process in a "dual" economic system
It may be said that the Italian economy has remained - after about three quarters of a century of industrial development along modern lines - roughly half “advanced” and half “primitive”.
V.C. LUTZ
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Redukcje świadomości i problem trzeciej drogi (Reductions of consciousness and the problem of a third way) [PDF]
The leading idea of the article is defined by a quotation from Fichte concerning the opposition between idealism and “dogmatism”, or naturalism. That opposition is interpreted as a result of two alternative “reductions of consciousness”: according to the
Małgorzata Kowalska
doaj
The Role of Necessity in Facing the Problem of Evil in Plato's Philosophy [PDF]
Plato, when dealing with the problem of evil, more than anything, tries to keep the good and the ideas transcendent and uninvolved in evil. Therefore, apart from the fact that he recognizes humans as the cause of some evil, he talks of a concept called ...
Mohammad Firuzkuhy +1 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

