Results 61 to 70 of about 137,479 (299)

Surface and form in contemporary architecture / Paviršius ir forma šiuolaikinėje architektūroje

open access: yesMokslas: Lietuvos Ateitis, 2012
Architectural form in contemporary architecture gains more and more independence and visual difference from the tectonic structure of the building. Many researchers of contemporary architecture separate a building’s “skin” from its carcass.
Algimantas M. Mačiulis
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A Stone Duality Between Finite Hypergraphs and FCTH-Lattices [PDF]

open access: yes, 2020
In this thesis we examine the relationship between hypergraphs and specialized frames called CTH-lattices. We find that these objects (under a finite context) and their associated homomorphisms form a duality, and therefore, are strongly related to each ...
Elrod, Stephen Jacob
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

DUALITY AND DILATON

open access: yesModern Physics Letters A, 1991
We review and elaborate on the issue of the dilaton transformation under the usual r → α′/r target space duality and its "non-static" generalization (or σ-model duality). It is found that the transformation law r → α′/r, [Formula: see text] which guarantees duality at the one-loop σ-model level should be modified at two (and higher) loop order.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Thermal duality and gravitational collapse [PDF]

open access: yes, 2014
Thermal duality is a relationship between the behaviour of heterotic string models of the E(8)xE(8) or SO(32) types at inversely related temperatures, a variant of T duality in the Euclidean regime.
Hewitt, M.
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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