Results 71 to 80 of about 103,825 (319)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

(0,2) Duality [PDF]

open access: yesAdvances in Theoretical and Mathematical Physics, 2003
We construct dual descriptions of (0,2) gauged linear sigma models. In some cases, the dual is a (0,2) Landau-Ginzburg theory, while in other cases, it is a non-linear sigma model. The duality map defines an analogue of mirror symmetry for (0,2) theories. Using the dual description, we determine the instanton corrected chiral ring for some illustrative
Adams, Allan   +2 more
openaire   +3 more sources

Sufficient optimality criteria and duality for multiobjective variational control problems with B-(p,r)-invex functions [PDF]

open access: yesOpuscula Mathematica, 2014
In this paper, we generalize the notion of \(B\)-\((p,r)\)-invexity introduced by Antczak in [A class of \(B\)-\((p; r)\)-invex functions and mathematical programming, J. Math. Anal. Appl. 286 (2003), 187-206] for scalar optimization problems to the case
Tadeusz Antczak, Manuel Arana Jiménez
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

DUALITY AND DILATON

open access: yesModern Physics Letters A, 1991
We review and elaborate on the issue of the dilaton transformation under the usual r → α′/r target space duality and its "non-static" generalization (or σ-model duality). It is found that the transformation law r → α′/r, [Formula: see text] which guarantees duality at the one-loop σ-model level should be modified at two (and higher) loop order.
openaire   +2 more sources

Human or Animal - Duality and Identity in Indra Sinha's Animal's People

open access: yesIndialogs: Spanish Journal of India Studies, 2018
This essay analyzes the figure of Animal in Indra Sinha's novel Animal's ...
Alex Girona Salmerón
doaj   +1 more source

Optimality and duality for nonsmooth semi-infinite E-convex multi-objective programming with support functions

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2020
In this paper, we study a nonsmooth semi-infinite multi-objective E-convex programming problem involving support functions. We derive sufficient optimality conditions for the primal problem.
Emam Tarek
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Monuments and monumentality: the cosmological model of the world of megaliths

open access: yesDocumenta Praehistorica, 2010
Neolithic monuments are physical and conceptual expressions of ideas about the nature of the world inhabited by early north European farmers. This contribution explores the complex symbolism encoded in megalithic architecture, and the socio-ritual ...
Magdalena S. Midgley
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Home - About - Disclaimer - Privacy