Results 71 to 80 of about 40,182 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Advances in Theoretical and Mathematical Physics, 2003 We construct dual descriptions of (0,2) gauged linear sigma models. In some cases, the dual is a (0,2) Landau-Ginzburg theory, while in other cases, it is a non-linear sigma model. The duality map defines an analogue of mirror symmetry for (0,2) theories. Using the dual description, we determine the instanton corrected chiral ring for some illustrative
Adams, Allan +2 more
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Modern Physics Letters A, 1991 We review and elaborate on the issue of the dilaton transformation under the usual r → α′/r target space duality and its "non-static" generalization (or σ-model duality). It is found that the transformation law r → α′/r, [Formula: see text] which guarantees duality at the one-loop σ-model level should be modified at two (and higher) loop order.
openaire +2 more sources
Quality selection in young oak stands
Journal of Forest Science, 2007 The paper deals with an experiment that was established at Opočno Experimental Station of the Forest and Game Management Research Institute (CR) in an oak small pole stage in 1952 to test whether Schaedelin'âs (1942) tending method worked out for beech
L. Chroust
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Being for the other: The asymmetrical Christology of Rowan Williams
Verbum et Ecclesia, 2020 What does it mean for the Christian Church to proclaim that God revealed Godself in Jesus Christ? This article tries to capture the answer given to this question by Rowans Williams, who defines and understands Christ as the ‘heart of creation’.
Auke L. Compaan
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source