Results 41 to 50 of about 69,844 (255)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Duality and fields redefinition in three dimensions

, 2004
We analyze local fields redefinition and duality for gauge field theories in three dimensions. We find that both Maxwell-Chern-Simons and the Self-Dual models admits the same fields redefinition. Maxwell-Proca action and its dual also share this property.
Deser S, Lemes V E R, Lemes V E R, M?rcio A M Gomes Landim R R, Marcio A M Gomes Landim R R, Márcio A M Gomes, Quevedo F, R R Landim   +7 more
core   +1 more source

Enhanced Gauge Symmetries and K3 Surfaces [PDF]

, 1995
String-string duality dictates that type IIA strings compactified on a K3 surface acquire non-abelian gauge groups for certain values of the K3 moduli. We argue that, contrary to expectation, the theories for which such enhanced gauge symmetries appear ...
Aspinwall, Aspinwall, Aspinwall, Aspinwall, Besse, Dixon, Dixon, Gepner, Greene, Harvey, Hull, Mukai, Narain, Nikulin, Paul S. Aspinwall, Seiberg, Sen, Strominger, Vafa, Witten, Witten   +20 more
core   +3 more sources

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Gauge symmetry of linearised Nordström gravity and the dual spin two field theory [PDF]

, 2022
V. A. Abakumova, Daniel Frolovsky, Hans-Christian Herbig, S. L. Lyakhovich   +3 more
openalex   +3 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Five-Dimensional Supersymmetric Gauge Theories and Degenerations of Calabi-Yau Spaces [PDF]

, 1997
We discuss five-dimensional supersymmetric gauge theories. An anomaly renders some theories inconsistent and others consistent only upon including a Wess-Zumino type Chern-Simons term.
Alvarez-Gaumé, Argyres, Aspinwall, Aspinwall, Aspinwall, Banks, Berglund, Bershadsky, Bershadsky, Cadavid, David R. Morrison, de Wit, Duff, Ferrara, Ferrara, Ganor, Ganor, Grauert, Harvey, Katz, Kawamata, Kawamata, Kenneth Intriligator, Kleiman, Klemm, Kollár, Mori, Morrison, Morrison, Morrison, Morrison, Mumford, Nathan Seiberg, Niemi, Redlich, Redlich, Reid, Sadov, Seiberg, Seiberg, Seiberg, Witten, Witten, Witten   +43 more
core   +4 more sources