Results 71 to 80 of about 71,442 (257)

Performance of Upper Limb module for Duchenne muscular dystrophy

Developmental Medicine & Child Neurology, 2020
To report the differences between Performance of Upper Limb (PUL) versions 1.2 and 2.0, compare the measurement ability of the two versions, and compare their longitudinal performance in Duchenne muscular dystrophy.
A. Mayhew, G. Coratti, E. Mazzone, K. Klingels, M. James, M. Pane, V. Straub, N. Goemans, E. Mercuri   +8 more
semanticscholar   +1 more source

High‐Adhesion Quadruple Hydrogen‐Bonded Ionogels: A Dual‐Function Platform for Gesture Recognition and Real‐Time NH3 Detection in Multiscenario

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Quadruple hydrogen‐bonded high‐adhesion ionogels for gesture recognition and real‐time NH3 sensing. Ionogels have garnered significant attention in flexible sensing due to their outstanding mechanical properties, conductivity, and stability. However, establishing a robust and stable adhesive interface with various substrates remains a significant ...
Haohao Lin, Xiaotong Ma, Zihao Chen, Long Yang, Zitong Kan, Ruochen An, Lin Xu, Zhiyong Chang   +7 more
wiley   +1 more source

Safety, feasibility, and efficacy of strengthening exercise in Duchenne muscular dystrophy

Muscle and Nerve, 2020
This two‐part study explored the safety, feasibility, and efficacy of a mild–moderate resistance isometric leg exercise program in ambulatory boys with Duchenne muscular dystrophy (DMD).
D. Lott, T. Taivassalo, K. Cooke, Hyunju Park, Zahra Moslemi, A. Batra, S. Forbes, B. Byrne, G. Walter, K. Vandenborne   +9 more
semanticscholar   +1 more source

City Slicker or Country Bumpkin?—Distinguishing Urban and Rural Residents From Subtle Facial Cues

European Journal of Social Psychology, EarlyView.
ABSTRACT Stereotypes characterize urban and rural residents as differing in traits, values and social outcomes. Here, we examined how people's stereotypes about urban and rural residents differ, testing their validity using a lens model. Results showed that participants detected whether people resided in urban or rural areas from photos across three ...
McLean G. Morgan, Laura Tian, Nicholas O. Rule   +2 more
wiley   +1 more source

Evolution of therapeutic management of patients with ANCA associated vasculitis in France after licensing Rituximab use

BMC Rheumatology
Introduction In 2013, rituximab was approved in France for the treatment of ANCA-associated vasculitis (AAV). The aim of the study was to compare the treatment and health events of adult incident patients with granulomatosis with polyangiitis (GPA) and ...
Cécile-Audrey Durel, Eric Simon Thervet, Dominique Chauveau, Aurélie Schmidt, Benjamin Terrier, Pierre M Bataille   +5 more
doaj   +1 more source

Duchenne muscular dystrophy

Nature Reviews Disease Primers, 2021
D. Duan, N. Goemans, S. Takeda, E. Mercuri, A. Aartsma-Rus   +4 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Being ambulatory does not secure respiratory functions of Duchenne patients

Annals of Indian Academy of Neurology, 2011
Aim: The aim of this work was to assess the respiratory functions of ambulatory Duchenne patients and to propose an earlier time period for intervention. Materials and Methods: Lung functions and North Star Ambulatory Assessment (NSAA) scores of Duchenne
Baris Ekici, Yakup Ergül, Burak Tatli, Feride Bilir, Fatih Binboga, Ayse Süleyman, Zeynep Tamay, Mine Çaliskan, Nermin Güler   +8 more
doaj   +1 more source

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment [PDF]

, 2020
Xu Liu, Yashuo Wang, Jennifer S. Gutierrez, Jesse M. Damsker, Kanneboyina Nagaraju, Eric P. Hoffman, Eric A. Ortlund   +6 more
openalex   +1 more source

Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

Nature Communications, 2017
Gene replacement therapies utilizing adeno-associated viral (AAV) vectors hold great promise for treating Duchenne muscular dystrophy (DMD). A related approach uses AAV vectors to edit specific regions of the DMD gene using CRISPR/Cas9.
N. Bengtsson, John K. Hall, G. Odom, Michael P. Phelps, Colin R. Andrus, R. D. Hawkins, S. Hauschka, J. Chamberlain, J. Chamberlain   +8 more
semanticscholar   +1 more source