Results 121 to 130 of about 103,945 (310)

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D, Arcidiacono, Pg, Capurso, G., Cardinale, V, Carpino, G, Doglioni, C, Gaudio, E, Pedica, F, Petrone, Mc, Severi, C, Zaccari, P   +10 more
core   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Universality of a mesenchymal transition signature in invasive solid cancers [PDF]

, 2012
In this brief communication, additional computational validation is provided consistent with the unifying hypothesis that a shared biological mechanism of mesenchymal transition, reflected by a precise gene expression signature, may be present in all ...
Dimitris Anastassiou
core   +1 more source

Predicting invasive breast cancer versus DCIS in different age groups. [PDF]

, 2014
BackgroundIncreasing focus on potentially unnecessary diagnosis and treatment of certain breast cancers prompted our investigation of whether clinical and mammographic features predictive of invasive breast cancer versus ductal carcinoma in situ (DCIS ...
Alagoz, Oguzhan, Ayvaci, Mehmet US, Burnside, Elizabeth S, Chhatwal, Jagpreet, Kerlikowske, Karla, Munoz del Rio, Alejandro, Nassif, Houssam, Sickles, Edward A   +7 more
core   +1 more source

MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Cancer Research, 2019
The mechanisms by which breast cancers progress from relatively indolent ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) are not well understood. However, this process is critical to the acquisition of metastatic potential.
Qianyu Guo, Vivian Z. Li, Jessica N. Nichol, F. Huang, William W. Yang, Samuel E. J. Preston, Zahra Talat, H. Lefrère, Henry Yu, Guihua Zhang, M. Basik, Christophe Gonçalves, Y. Zhan, D. Plourde, Jie Su, Jose Torres, M. Marques, Sara Al Habyan, K. Bijian, F. Amant, M. Witcher, F. Behbod, L. McCaffrey, M. Alaoui-Jamali, N. Giannakopoulos, M. Brackstone, L. Postovit, S. D. Del Rincon, W. Miller   +28 more
semanticscholar   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

A rare case of extensive ductal carcinoma in situ of the breast with secretory features

Rare Tumors, 2012
We report a very rare case of extensive ductal carcinoma in situ (DCIS) of the breast with secretory features in a 30-year old Japanese woman. The patient presented with a nodule in the lower inner quadrant of the left breast measuring approximately 2-3 ...
Kenichi Sugihara, Tsuyoshi Nakagawa, Shigeo Kawai, Takeo Iwama, Akira Iwasaki, Takanobu Sato   +5 more
doaj   +1 more source

Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8a1 and human ch13q34 [PDF]

, 2007
Serial analysis of gene expression from aggressive mammary tumors derived from transplantable p53 null mouse mammary outgrowth lines revealed significant up-regulation of Tfdp1 (transcription factor Dp1), Lamp1 (lysosomal membrane glycoprotein 1) and ...
Abba, Martín Carlos, Aldaz, Claudio Marcelo, Cai, Wei Wen, Donehower, Lawrence A., Fabris, Victoria Teresa, Hu, Yuhui, Kittrell, Frances S., Medina, Daniel, Sahin, Aysegui   +8 more
core   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Case Report: Ductal Carcinoma In Situ in the Male Breast

Case Reports in Radiology, 2012
High-grade ductal carcinoma in situ is incredibly rare in male patients. The prognosis for ductal carcinoma in situ (DCIS) in a male patient is the same as it would be for a female with the same stage disease; therefore, early recognition and diagnosis ...
Joshua Chern, Lydia Liao, Raymond Baraldi, Elizabeth Tinney, Karen Hendershott, Pauline Germaine   +5 more
doaj   +1 more source