Results 181 to 190 of about 53,802 (245)
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
The impact of immune microenvironment on local control of ductal carcinoma in situ receiving breast conservative therapy. [PDF]
Xu FF +6 more
europepmc +1 more source
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu +4 more
wiley +1 more source
Semaphorin-7A promotes macrophage-mediated mammary epithelial and ductal carcinoma in situ invasion. [PDF]
Dahms PA +4 more
europepmc +1 more source
Cell membrane‐coated nanoparticles for dermatological diseases
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley +1 more source
Diagnostic value of automated breast volume scanner for breast ductal carcinoma in situ. [PDF]
Tian C, Wu J, Wang Z.
europepmc +1 more source
Clinical features and multimodal imaging were analyzed for nipple discharge without palpable masses. MRI shows the highest diagnostic sensitivity and reliable surgical localization. Bloody/yellow discharge, along with positive ultrasound and MRI findings, informs risk stratification and surgical intervention.
Yang Yang +9 more
wiley +1 more source
Radiation therapy in a ductal carcinoma in situ patient with ornithine transcarbamylase deficiency: a case report. [PDF]
Kang I +10 more
europepmc +1 more source
ABSTRACT Cholangiocarcinoma (CCA) remains a difficult‐to‐treat biliary malignancy in which therapeutic stratification increasingly depends on predictive biomarkers. Although next‐generation sequencing is essential for the detection of targetable genomic alterations, immunohistochemistry (IHC) retains a practical role because it is widely available ...
Francesco Vasuri +3 more
wiley +1 more source
The landscape of the intestinal microbiome among patients with newly diagnosed invasive breast cancer and ductal carcinoma in situ (DCIS). [PDF]
Sammons SL +17 more
europepmc +1 more source

