Results 181 to 190 of about 53,802 (245)

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao   +4 more
wiley   +1 more source

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

open access: yesPrecision Radiation Oncology, Volume 10, Issue 2, Page 192-204, June 2026.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu   +4 more
wiley   +1 more source

Cell membrane‐coated nanoparticles for dermatological diseases

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Clinical and Imaging Characteristics in the Diagnosis and Surgical Management of Nipple Discharge Without Clinically Palpable Masses: A Retrospective Cohort Study

open access: yesThoracic Cancer, Volume 17, Issue 12, June 2026.
Clinical features and multimodal imaging were analyzed for nipple discharge without palpable masses. MRI shows the highest diagnostic sensitivity and reliable surgical localization. Bloody/yellow discharge, along with positive ultrasound and MRI findings, informs risk stratification and surgical intervention.
Yang Yang   +9 more
wiley   +1 more source

Radiation therapy in a ductal carcinoma in situ patient with ornithine transcarbamylase deficiency: a case report. [PDF]

open access: yesRadiat Oncol J
Kang I   +10 more
europepmc   +1 more source

Predictive Immunohistochemistry in Cholangiocarcinoma: Current Clinical Utility, Practical Limitations, and Emerging Directions

open access: yesAPMIS, Volume 134, Issue 6, June 2026.
ABSTRACT Cholangiocarcinoma (CCA) remains a difficult‐to‐treat biliary malignancy in which therapeutic stratification increasingly depends on predictive biomarkers. Although next‐generation sequencing is essential for the detection of targetable genomic alterations, immunohistochemistry (IHC) retains a practical role because it is widely available ...
Francesco Vasuri   +3 more
wiley   +1 more source

The landscape of the intestinal microbiome among patients with newly diagnosed invasive breast cancer and ductal carcinoma in situ (DCIS). [PDF]

open access: yesNPJ Breast Cancer
Sammons SL   +17 more
europepmc   +1 more source

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