Results 161 to 170 of about 85,355 (254)

Multi‐Omics and Machine Learning‐Uncovered FLT1‐Mediated Epithelial‐Endothelial Crosstalk in Cellular Senescence Driving Clear Cell Renal Cell Carcinoma Malignancy

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
This study integrates multi‐omics data and machine learning to reveal FLT1 as a central mediator of epithelial‐endothelial crosstalk in clear cell renal cell carcinoma (ccRCC). We demonstrate that FLT1‐associated signaling promotes a senescence‐enriched tumor microenvironment, driving malignant progression. Spatial and single‐cell analyses confirm FLT1
Mouyuan Sun, Huchao Mao, Yaxian Luo, Mei Yang, Zhixu He, Shuangyang Li, Zhichao Liu, Lianjie Peng, Quanjie Zhang, Jingyu Zhang, Yan Zhang   +10 more
wiley   +1 more source

Margin of Error: The Emerging Role of Field Cancerization in Predicting Recurrence Risk of Ductal Carcinoma In Situ. [PDF]

Int J Mol Sci
Hu-Lieskovan S, Banks O, Davidson R, Franklin D, Rida P, Jinna N.   +5 more
europepmc   +1 more source

Ductal carcinoma in situ

, 2020
null Linda Moy, MD, null Linda Du, DO, MPH   +1 more
openaire   +2 more sources

Challenges in the future of cancer screening

International Journal of Cancer, Volume 158, Issue 8, Page 2013-2022, 15 April 2026.
Abstract The purpose of cancer screening is to reduce mortality, and ideally incidence, from the cancer screened for. Until recently, cancer screening has been offered to all persons in pre‐defined sex‐ and age‐groups. The exception is lung screening which is targeted to high‐risk individuals.
Elsebeth Lynge, Berit Andersen, Stig E. Bojesen, Lone Kjeld Petersen, Mickael Bech, Martin Bøgsted, Mie Seest Dam, Søren Egstrand, Anne Mette Fløe Hvass, Camilla J. Kobylecki, Kristina Lång, Mads Nielsen, Giorgi Paolo Rossi, Michael Stenger, Ilse Vejborg, Future of Cancer Screening Working Group, Vibe Munk Bertelsen, Janne Bigaard, Karen Omann Binderup, Lennart Friis‐Hansen, Stine Bisgaard Greve, Jessica Xin Hjaltelin, Rikke Hedegaard Jensen, Gitte Jessing, Pia Kirkegaard, Mette Hartmann Nonboe, Tina Bech Olesen, Katrine Stolberg, Signe Bülow Therkildsen, Mette Kielsholm Thomsen   +29 more
wiley   +1 more source

Multiparametric Breast MRI for the Differentiation of Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ in Postmenopausal Women. [PDF]

Cureus
Mihajlovic MN, Raspopovic LJ, Dimitrijevic D, Krusac IB, Djajic A, Nadrljanski MM.   +5 more
europepmc   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Spatially Discontinuous Mutation Topographies in Ductal Carcinoma In Situ Reveal Noncompetitive Growth Dynamics. [PDF]

Cancer Res
Ryser MD, Greenwald MA, Monyak D, Sorribes IC, King L, Hall A, Geradts J, Weaver DL, Mallo D, Holloway ST, Wu E, Murgas KA, West RB, Grimm LJ, Maley CC, Marks JR, Shibata D, Hwang ES.   +17 more
europepmc   +1 more source

Antipsychotic-Associated Galactorrhea May Mask Diffuse Ductal Carcinoma in Situ: A Diagnostic Challenge. [PDF]

Cureus
Engele I, Zablocka T, Asere E, Eglitis J.   +3 more
europepmc   +1 more source

The impact of immune microenvironment on local control of ductal carcinoma in situ receiving breast conservative therapy. [PDF]

Breast Cancer Res
Xu FF, Zheng SF, Shao ZY, Qi WX, Cao L, Wang CF, Chen JY.   +6 more
europepmc   +1 more source

Semaphorin-7A promotes macrophage-mediated mammary epithelial and ductal carcinoma in situ invasion. [PDF]

Breast Cancer Res
Dahms PA, Hinckley B, Prekeris R, Behbod F, Lyons TR.   +4 more
europepmc   +1 more source