Results 41 to 50 of about 103,945 (310)

Can Molecular Biomarkers Help Reduce the Overtreatment of DCIS?

Current Oncology, 2023
Ductal carcinoma in situ (DCIS), especially in the era of mammographic screening, is a commonly diagnosed breast tumor. Despite the low breast cancer mortality risk, management with breast conserving surgery (BCS) and radiotherapy (RT) is the prevailing ...
Ezra Hahn, Danielle Rodin, Rinku Sutradhar, Sharon Nofech-Mozes, Sabina Trebinjac, Lawrence Frank Paszat, Eileen Rakovitch   +6 more
doaj   +1 more source

Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast

Breast Cancer Research, 2020
The immune microenvironment in ductal carcinoma in situ (DCIS) and its significance are not well established. This study was conducted to evaluate the immune microenvironment of DCIS including the composition of tumor-infiltrating lymphocyte (TIL ...
Milim Kim, Yul Ri Chung, Hyun Jeong Kim, J. Woo, Soomin Ahn, S. Y. Park   +5 more
semanticscholar   +1 more source

Metastatic Prostate Cancer Synchronous with Male Breast Papillary Ductal Carcinoma in situ: Management Dilemma and Literature Review

Case Reports in Oncology, 2021
Prostate cancer is common in men, but tumour of the male breast is rare. For these two tumours to be presented synchronously in a male patient is even rarer.
H. H. Hasbullah, Farah Wahida MdYusof, Amirah Hayati Ahmad, O. Alzallal, S. E. T. T Sharif   +4 more
semanticscholar   +1 more source

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma [PDF]

, 2007
Aims: To clarify MUC1 patterns in invasive ductal breast carcinoma and to relate them to clinicopathological parameters, coexpression of other biological markers and prognosis.
Arnerlov C, Berry N, Camp RL, Croce MV, Gendler S, Gendler SJ, Hayes DF, Hilkens J, Kohlgraf KG, Ligtenberg MJ, Wesseling J   +10 more
core   +2 more sources

Ductal Carcinoma In Situ

Hematology/Oncology Clinics of North America
In breast cancer (BC) pathogenesis models, normal cells acquire somatic mutations and there is a stepwise progression from high-risk lesions and ductal carcinoma in situ to invasive cancer. The precancer biology of mammary tissue warrants better characterization to understand how different BC subtypes emerge.
Bychkovsky, Brittany L., Myers, Sara, Warren, Laura E. G., De Placido, Pietro, Parsons, Heather A.   +4 more
openaire   +4 more sources

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast

medRxiv, 2020
In a substantial number of patients, ductal carcinoma in situ (DCIS) of the breast will never progress to invasive ductal carcinoma, and these patients are often overtreated under the current clinical criteria.
Satoi Nagasawa, Yuta Kuze, I. Maeda, Y. Kojima, A. Motoyoshi, T. Onishi, T. Iwatani, Takamichi Yokoe, J. Koike, M. Chosokabe, Manabu Kubota, Hibiki Seino, A. Suzuki, M. Seki, K. Tsuchihara, Eisuke Inoue, K. Tsugawa, T. Ohta, Yutaka Suzuki   +18 more
semanticscholar   +1 more source

Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Ductal Carcinoma In Situ

Annals of Surgical Oncology, 2016
PurposeControversy exists regarding the optimal negative margin width for ductal carcinoma in situ (DCIS) treated with breast-conserving surgery and whole-breast irradiation.MethodsA multidisciplinary consensus panel used a meta-analysis of margin width ...
M. Morrow, K. V. Van Zee, L. Solin, N. Houssami, M. Chávez-MacGregor, Jay R Harris, J. Horton, Shelley Hwang, Peggy L. Johnson, M. Marinovich, S. Schnitt, Irene L. Wapnir, Meena S. Moran   +12 more
semanticscholar   +1 more source

Evaluation of survivin immunoexpression in the differentiation of high- and low-grade breast ductal carcinoma in situ

Einstein (São Paulo)
Objective To evaluate the expression of survivin protein in low- and high-grade ductal carcinoma in situ. Methods Breast tissue fragments obtained by incisional biopsy and surgical procedures of 37 women with ductal carcinoma in situ of the breast were ...
Milca Cezar Chade, Sebastião Piato, Maria Antonieta Longo Galvão, José Mendes Aldrighi, Rômulo Negrini, Evandro Falaci Mateus, Enio Martins Medeiros   +6 more
doaj   +1 more source

The Baader-Meinhof phenomenon in ductal carcinoma in situ of the breast [PDF]

, 2016
Sir: We read with interest the review of Pang et al. published in the annual review issue of Histopathology in January 2016, entitled ‘Ductal carcinoma in situ—update on risk assessment and management’, wherein a concise overview of the diagnosis and ...
Floris, Giuseppe, Lambein, Kathleen, Libbrecht, Louis, Van Bockstal, Mieke   +3 more
core   +2 more sources

Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance

Signal Transduction and Targeted Therapy
Ductal carcinoma in situ (DCIS) represents pre-invasive breast carcinoma. In untreated cases, 25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in distinguishing between non-progressive and progressive DCIS, often resulting in ...
Jing Wang, Baizhou Li, Meng Luo, Jia Huang, Kun Zhang, Shu Zheng, Suzhan Zhang, Jiaojiao Zhou   +7 more
semanticscholar   +1 more source