Mucocele like Tumour of the Breast Associated with Ductal Carcinoma in situ and Focal Ductal Carcinoma: What is the Best Approach to these Patients? [PDF]
Mucocele Like Tumours (MLT) of the breast are quite rare neoplasms displaying a broad spectrum. These lesions were considered benign initially. But now, they are believed to be related to atypical ductal hyperplasia, ductal carcinoma, or mucinous ...
Serdar Altinay+3 more
doaj +1 more source
A Computer-Aided Diagnosis System for Breast Pathology: A Deep Learning Approach with Model Interpretability from Pathological Perspective [PDF]
Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification from the convolutional neural networks (CNN) are demonstrated in this study to provide comprehensive ...
arxiv
Ductal carcinoma in situ of the breast [PDF]
Ductal carcinoma in situ (DCIS) of the breast is a noninvasive form of breast cancer that has increased in incidence over the past several decades secondary to screening mammography. DCIS now represents 20–30% of all newly diagnosed cases of breast cancer.
Steven J. Buskirk+3 more
openaire +2 more sources
Introduction The partial estrogen-agonist action of tamoxifen on bone receptors has beneficial effects on bone mineral density. However, in premenopausal women, the use of tamoxifen causes systemic estrogen depletion, which has detrimental effects on ...
Dooreh Kim+5 more
semanticscholar +1 more source
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
BACKGROUND A better definition of biomarkers and biological processes related to local recurrence and disease progression is highly warranted for ductal breast carcinoma in situ (DCIS).
C. Strell+19 more
semanticscholar +1 more source
Effects of patient selection on the applicability of results from a randomised clinical trial (EORTC 10853) investigating breast-conserving therapy for DCIS [PDF]
Selection of patients for randomised clinical trials may have a large impact on the applicability of the study results to the general population presenting the same disorder.
A A M Hart+35 more
core +3 more sources
Toward 3D‐Bioprinted Models of the Liver to Boost Drug Development
During preclinical studies, bidimensional in vitro models and animal models are synergically exploited to forecast safety and efficacy. 3D‐bioprinting is exploited to produce complex in vitro models, able to mimic physiological and pathological conditions, thus aiming to overcome the conventional paradigm.
Giuseppe Guagliano+5 more
wiley +1 more source
Avaliação da resposta inflamatória sistêmica induzida por carcinoma ductal in situ em cadelas
Em tumores mamários, é comum alterações inflamatórias, causadas principalmente em neoplasias que metastatizam. Este trabalho tem por objetivo avaliar a concentração de Proteína C Reativa, correlacionada as alterações de proteínas totais e albumina em ...
Paulo Henrique +5 more
doaj +1 more source
Matrix Metalloproteinase 13 Is Induced in Fibroblasts in Polyomavirus Middle T Antigen-Driven Mammary Carcinoma without Influencing Tumor Progression [PDF]
Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that is induced in myofibroblasts during the earliest invasive stages of human breast carcinoma, suggesting that it is involved in tumor progression.
Askautrud, Hanne A.+9 more
core +3 more sources
Abstract Introduction Oncoplastic breast surgery following breast conservation surgery (BCS) utilizes aesthetic breast reduction techniques, and these reconstructions entail either volume displacement or volume replacement depending on the size and location of the excised tumor.
Neta Adler+3 more
wiley +1 more source