Results 111 to 120 of about 470,995 (357)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Increased Prevalence of Colorectal Neoplasia in Korean Patients with Sporadic Duodenal Adenomas: A Case-Control Study

Gut and Liver, 2011
Background/AimsRecent data from Western populations have suggested that patients with sporadic duodenal adenomas are at a higher risk for the development of colorectal neoplasia.
doaj   +1 more source

Synchronous gastric and duodenal metastases from head and neck squamous cell carcinoma: a unique presentation of upper gastrointestinal bleeding. [PDF]

, 2018
Metastatic disease to the stomach or duodenum is an infrequent diagnosis, and head and neck squamous cell carcinoma (HNSCC) is one of the least common primary malignancies that lead to gastric or duodenal metastases.
Daitch, Zachary, Jiang, Wei, Kistler, Charles Andrew, Quirk, Daniel M., Tarangelo, Nicholas P.   +4 more
core   +1 more source

Serotonin- and Somatostatin-Positive Goblet Cell Carcinoid of the Duodenum [PDF]

, 2012
In the duodenum, mixed exocrine-endocrine tumors exhibiting both neuroendocrine and glandular differentiations [cf. appendiceal goblet cell carcinoids (GCCs)] are rare.
Hase, Kazuo, Kaga, Hitoshi, Matsuzaki, Koji, Niihara, Naoko, Ogata, Sho, Ogawa, Tomomichi, Ohara, Ichiyou, Okusa, Yasushi, Tominaga, Susumu   +8 more
core   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Nutritional benefits of pancreas‐sparing total duodenectomy for severe duodenal polyposis in patients with familial adenomatous polyposis

Annals of Gastroenterological Surgery
Aim Severe duodenal polyposis associated with familial adenomatous polyposis considerably increases the risk of duodenal cancer. Pancreas‐sparing total duodenectomy is an alternative surgical approach for managing severe duodenal polyposis.
Ibuki Fujinuma, Toshiro Ogura, Ayano Takahashi, Satoshi Nomura, Kei Kitamura, Amane Takahashi, Takehiro Shiraishi, Yoshiko Mori, Toru Ishiguro, Takatoshi Matsuyama, Youichi Kumagai, Hideyuki Ishida   +11 more
doaj   +1 more source

A Case of Malignant Melanoma Metastasis in the Ileal Conduit

IJU Case Reports, EarlyView.
ABSTRACT Introduction Tumor development in the ileal conduit is rare. Herein, we present a case of metastatic malignant melanoma occurring within the ileal conduit 17 years after radical cystectomy. Case Presentation A 76‐year‐old Japanese man, with a history of bladder cancer treated with radical cystectomy and ileal conduit diversion, presented with ...
Noritoshi Shamoto, Yushi Naito, Yuta Sano, Kazuna Matsuo, Satoshi Inoue, Tomoyasu Sano, Tomokazu Kimura, Shohei Ishida, Yoshihisa Matsukawa, Shusuke Akamatsu   +9 more
wiley   +1 more source

Small bowel neuroendocrine tumors: from pathophysiology to clinical approach [PDF]

, 2016
Neuroendocrine tumors (NETs), defined as epithelial tumors with predominant neuroendocrine differentiation, are among the most frequent types of small bowel neoplasm.
Cotter, José, Rosa, Bruno, Xavier, Sofia   +2 more
core   +1 more source

Immunoglobulin G4‐Related Inflammatory Pseudotumor With Cystic Features Mimicking Renal Cancer

IJU Case Reports, EarlyView.
ABSTRACT Introduction Immunoglobulin G4‐related disease is a systemic fibroinflammatory disorder that affects the kidney, presenting as an immunoglobulin G4‐related inflammatory pseudotumor. These renal inflammatory pseudotumors are usually solid, and cystic presentations have not been previously described. Case Presentation We report a 77‐year‐old man
Yuki Tanaka, Takahisa Yamashita, Kazuki Yokota, Kenta Fujii, Sachi Kitayama, Shoichi Nagamoto, Hideki Takeshita, Yohei Okada, Satoru Kawakami, Akihiro Yano   +9 more
wiley   +1 more source

Robot‐Assisted Radical Nephrectomy for Renal Cell Carcinoma in a Right Intrathoracic Kidney Following Congenital Diaphragmatic Hernia Repair: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Congenital diaphragmatic hernia (CDH) can result in intrathoracic displacement of the kidney, presenting anatomical challenges for robot‐assisted radical nephrectomy (RARN). Reports of RARN in such cases are scarce. Case Presentation A 56‐year‐old man with a history of right‐sided CDH repair was referred for evaluation of an ...
Yutaro Sasaki, Saki Kobayashi, Fumiya Kadoriku, Kei Daizumoto, Ryotaro Tomida, Yoshito Kusuhara, Tomoya Fukawa, Kunihisa Yamaguchi, Yasuyo Yamamoto, Junya Furukawa   +9 more
wiley   +1 more source