Results 161 to 170 of about 16,542 (247)
International Journal of Dermatology, EarlyView.The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino +8 more
wiley +1 more source
Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis
International Journal of Dermatology, EarlyView.Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller +11 more
wiley +1 more source
Treatment‐Associated Type 2/22 Helper T‐Cell States in Dupilumab‐Treated Atopic Dermatitis
Clinical &Experimental Allergy, EarlyView.
Mai Nishimura +5 more
wiley +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
Immunology &Cell Biology, EarlyView.IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Tralokinumab Versus Dupilumab for the Treatment of Atopic Dermatitis with Moderate-to-Severe Hand Involvement: A Matching-Adjusted Indirect Comparison. [PDF]
Dermatol Ther (Heidelb)Armstrong A +11 more
europepmc +1 more source
Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria
Journal of the European Academy of Dermatology and Venereology, EarlyView.This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran +2 more
wiley +1 more source
Real-world infection outcomes and disparities with dupilumab use in allergic rhinitis. [PDF]
Ann Allergy Asthma ImmunolRuran HB +4 more
europepmc +1 more source
European consensus recommendations for nummular eczema: A modified Delphi study
Journal of the European Academy of Dermatology and Venereology, EarlyView.The first consensus recommendations for nummular eczema are based on an international modified Delphi study. Sixty‐three experts from 16 countries evaluated 64 statements addressing definition, diagnosis, assessment and treatment. Consensus supports clinical diagnosis, individualized long‐term management, topical and selected systemic therapies, while ...
Mette Deleuran +6 more
wiley +1 more source