Results 181 to 190 of about 16,542 (247)

Pediatric Lichen Planus Pemphigoides in a Child With Sickle Cell Disease: Cyclosporine Induction and Dupilumab Maintenance

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Lichen planus pemphigoides (LPP) is a rare autoimmune subepidermal blistering disorder that combines lichenoid lesions of lichen planus with immunopathologic features of pemphigoid disease. We report an 8‐year‐old boy with homozygous sickle cell disease and severe atopic dermatitis who developed diffuse pruritic violaceous papules followed by ...
Yumeng T. Engelking   +3 more
wiley   +1 more source

Pediatric Eosinophil-Predominant Collagenous Gastritis: From Conventional Therapy to Dupilumab: A Case Report. [PDF]

open access: yesReports (MDPI)
Rogalidou M   +7 more
europepmc   +1 more source

Health‐Care Burden of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Hong Kong in the Post‐COVID Pandemic Era—Impact of Phenotype and Exacerbation History

open access: yesPublic Health Challenges, Volume 5, Issue 4, December 2026.
There was an increase in the AECOPD admission numbers after the COVID‐19 pandemic, resulting in increase in health economic burden. ABSTRACT Rationale Chronic obstructive pulmonary disease (COPD) is known to be associated with substantial health‐care utilization and economic costs.
Wang Chun Kwok   +6 more
wiley   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, Volume 53, Issue 12, Page 1165-1171, December 2026.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Computed tomography-derived pulmonary blood volume distribution may be modifiable in asthma. [PDF]

open access: yesERJ Open Res
Mappanasingam AA   +12 more
europepmc   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, Volume 117, Issue 6, Page 1485-1499, December 2026.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Dupilumab for Drug-Induced Bullous Pemphigoid: A Case Series and Literature Review. [PDF]

open access: yesClin Cosmet Investig Dermatol
Sakpuwadol N   +3 more
europepmc   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

open access: yesImmunology, Volume 179, Issue 4, Page 565-578, December 2026.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang   +9 more
wiley   +1 more source

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