Results 61 to 70 of about 23,326 (221)

Long-term dupilumab treatment for chronic refractory generalized prurigo nodularis: A retrospective cohort study [PDF]

, 2021
Jorge R. Georgakopoulos, David Croitoru, Tina Felfeli, Raed Alhusayen, Perla Lansang, Neil H. Shear, Jensen Yeung, Scott R. Walsh   +7 more
openalex   +1 more source

Immunoglobulin G; structure and functional implications of different subclass modifications in initiation and resolution of allergy. [PDF]

, 2017
IgE and not IgG is usually associated with allergy. IgE lodged on mast cells in skin or gut and basophils in the blood allows for the prolonged duration of allergy through the persistent expression of high affinity IgE receptors.
Amlot P. L., Concha L. B., Delves P. J., Edkins A., Finkelman F. D., Hazenbos W. L., Huizinga T. W., Lessof M. H., Mauro M., McConnell T. H., McMenamin C., Mosmann T. R., Palmeira P., Platts‐Mills T. A., Ren R., Schandane L., Tiseo P. J., Van Der Zee J. S., Yang F.   +18 more
core   +2 more sources

A case of recurrent chronic eosinophilic pneumonia after switching from benralizumab to dupilumab

Respiratory Medicine Case Reports
Dupilumab inhibits interleukin-4Rα and suppresses type 2 inflammation. Careful administration of dupilumab is required because it increases the blood eosinophil count secondary to a decrease in local eosinophil counts, sometimes resulting in eosinophilic
Daiki Nakashima, Eri Mori, Nobuyoshi Otori   +2 more
doaj   +1 more source

The Application of Dupilumab to Pediatric Patients Aged 6–11yrs with Moderate-to-Severe Atopic Dermatitis Whose Disease is Not Adequately Controlled: The Clinical Data so Far

Drug Design, Development and Therapy, 2023
Sarah Balboul,1 Julia Kahn,1 Alexis Tracy,2 Anjelica Peacock,3 Abigail Cline2– 4 1School of Medicine, New York Medical College, Valhalla, NY, USA; 2Department of Dermatology, New York Medical College, Valhalla, NY, USA; 3Department of Dermatology ...
Balboul S, Kahn J, Tracy A, Peacock A, Cline A   +4 more
doaj  

Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma

, 2019
Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean, Brusselle, Guy, Buhl, Roland, Katsaounou, Paraskevi, Martinez, Rafael, Pfister, Pascal, Wahn, Ulrich   +6 more
core   +1 more source

Research highlights from the 2018 European Respiratory Society International Congress: Airway disease [PDF]

, 2010
The annual European Respiratory Society (ERS) International Congress (held in Paris in 2018) was once again a platform for discussion of the highest-quality scientific research, cutting-edge techniques and innovative new therapies within the respiratory ...
Andersson, Cecilia, Bikov, Andras, Bonvini, Sara J., Lopez-Campos Bodineau, Jose Luis, Mathioudakis, Alexander G., McDonnell, Melissa, Schleich, Florence   +6 more
core   +1 more source

Long-term efficacy and safety of dupilumab with concomitant topical corticosteroids in Japanese pediatric patients with moderate-to-severe atopic dermatitis: Results from a phase 3 open-label extension study

Allergology International
Background: Dupilumab is approved in Japan for the treatment of atopic dermatitis in patients aged 6 months to 18 years. However, long-term data are lacking in this patient population. Here we report the final analysis of a long-term open-label extension
Yoko Kataoka, Motohiro Ebisawa, Akio Tanaka, Mizuho Nagao, Elizabeth Laws, Hisakatsu Nawata, Kazuhiko Arima, Daisuke Watanabe, Xin Lu, Jennifer Maloney, Ariane Dubost-Brama, Ashish Bansal, Kenji Yahata   +12 more
doaj   +1 more source

The use of dupilumab in severe atopic dermatitis during pregnancy: a case report

Allergy, Asthma & Clinical Immunology, 2022
Background Atopic dermatitis is a common chronic skin disease that can occur in pregnancy. Current treatments include topical and systemic glucocorticoids and cyclosporine.
Nabeel H. Akhtar, Touraj Khosravi-Hafshejani, Daud Akhtar, Gurbir Dhadwal, Amin Kanani   +4 more
doaj   +1 more source

Human and computational models of atopic dermatitis:A review and perspectives by an expert panel of the International Eczema Council [PDF]

, 2018
Atopic dermatitis (AD) is a prevalent disease worldwide and is associated with systemic comorbidities representing a significant burden on patients, their families, and society. Therapeutic options for AD remain limited, in part because of a lack of well-
Bieber, Thomas, Bissonette, Robert, Brown, Sara J., Dhar, Sandipan, Eyerich, Kilian, Guttman-Yassky, Emma, Hijnen, Dirk J., Irvine, Alan, Paller, Amy S., Perez White, Bethany E., Reynolds, Nick J., Tanaka, Reiko J., Thyssen, Jacob P., Vestergaard, Christian, Werfel, Thomas, Wollenberg, Andreas   +15 more
core   +5 more sources

Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation [PDF]

, 2019
Millions of people worldwide are suffering from allergic inflammatory airway disorders. These conditions are regarded as a consequence of multiple imbalanced immune events resulting in an inadequate response with the exact underlying mechanisms still ...
Duerr, Claudia U., Fritz, Jörg H., Helfrich, Sofia, Mindt, Barbara C.   +3 more
core   +1 more source