Results 81 to 90 of about 16,542 (247)

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

open access: yesJEADV Clinical Practice, EarlyView.
Skin samples of Hailey‐Hailey and Darier diseases were analyzed for inflammatory and barrier markers using indirect immunofluorescence and transcriptomic techniques. A mixed Th2/Th17 inflammatory pattern and altered expression of barrier markers were observed.
Ella Glodjajic   +10 more
wiley   +1 more source

Dupilumab for recalcitrant prurigo nodularis: Case report

open access: yes, 2022
Dupilumab is a recombinant fully human monoclonal antibody modulating the signaling of the interleukin (IL)—4 and IL-13 pathways and has been approved for the treatment of moderate/severe atopic dermatitis.
Joel Reis, Inês Raposo, Manuela Selores
core  

Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense   +4 more
wiley   +1 more source

Dupilumab for Chronic Rhinosinusitis with Primary Nasal Polyps: a Case Report and Literature Review [PDF]

open access: yes
Mingrui Deng, Rao Fu, Mei Lv, Ya Feng Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of ChinaCorrespondence: Mei Lv, Department of ...
Fu R, Lv M, Feng Y, Deng M
core  

Dupilumab and Alopecia Areata

open access: yes
Some providers have used dupilumab off-label for the treatment of recalcitrant alopecia areata, particularly in patients with atopic dermatitis. However, many clinicians have noted mixed results, with some patients reporting improvement while other ...
Srivatsa, Anagha
core   +1 more source

Supplementary tables for "Cutaneous T-cell lymphoma following dupilumab use: A systematic review"

open access: yes, 2022
In this systematic review, we aimed to evaluate reported cases of CTLC following dupilumab use and identify characteristics, histologic findings, and timeline of CTCL development. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)
Park, A (via Mendeley Data), Park, Ariel
core   +1 more source

Trends in the Asthma Burden Attributable to High Body Mass Index in Children Across 204 Countries and Territories, 1990–2021: An Analysis of the 2021 Global Burden of Disease Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT High body mass index (BMI) has been identified as a significant risk factor for childhood asthma. Given the rising prevalence of childhood obesity, assessing the impact of high BMI on asthma burden trends is imperative. Utilizing Global Burden of Disease (GBD) data, we estimated age‐, sex‐, geography‐, and sociodemographic index (SDI ...
Hua Li   +4 more
wiley   +1 more source

Long-term mortality outcomes among immunotherapy recipients treated with dupilumab for the management of cutaneous immune-related adverse events

open access: yesJournal for ImmunoTherapy of Cancer
Background Dupilumab has been added to National Cancer Comprehensive Network guidelines as a therapeutic strategy for managing certain cutaneous immune-related adverse events (cirAEs) from immune checkpoint blockade (ICB).
Shadmehr Demehri   +13 more
doaj   +1 more source

Efficacy of Endoscopic Sinus Surgery for Allergic Fungal Rhinosinusitis: A Systematic Review With Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Endoscopic sinus surgery (ESS) plays a central role in the management of allergic fungal rhinosinusitis (AFRS); however, outcomes vary across studies. The goal of this study is to systematically review and synthesize evidence on the outcomes of ESS in patients with AFRS.
Amani Kais   +4 more
wiley   +1 more source

Atopic dermatitis and attention‐deficit/hyperactivity disorder comorbidity in children and adolescents: Epidemiology, mechanisms, and clinical management

open access: yesPediatric Investigation, EarlyView.
This review synthesizes epidemiological evidence linking atopic dermatitis to attention‐deficit/hyperactivity disorder in children, proposes an “inflammation‐itch‐neurobehavioral axis” integrating sleep disruption, neuroendocrine dysregulation, and emerging neuro‐immune circuits, and outlines multidisciplinary management strategies targeting both skin ...
Qingyang Zhao   +11 more
wiley   +1 more source

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