Results 91 to 100 of about 15,263 (254)

Dupilumab for Chronic Rhinosinusitis with Primary Nasal Polyps: a Case Report and Literature Review [PDF]

Mingrui Deng, Rao Fu, Mei Lv, Ya Feng Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of ChinaCorrespondence: Mei Lv, Department of ...
Fu R, Lv M, Feng Y, Deng M
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Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source

Dupilumab Reduces Urticaria Activity, Itch, and Hives in Patients with Chronic Spontaneous Urticaria Regardless of Baseline Serum Immunoglobulin E Levels

Dermatology and Therapy
Introduction In chronic spontaneous urticaria (CSU), interleukin (IL)-4 and IL-13 may promote mast cell activation directly via IL-4 receptor expression, or indirectly via upregulated immunoglobulin E (IgE) production.
Marcus Maurer, Thomas B. Casale, Sarbjit S. Saini, Moshe Ben-Shoshan, Elizabeth Laws, Jennifer Maloney, Deborah Bauer, Allen Radin, Melanie Makhija   +8 more
doaj   +1 more source

Dupilumab side effect in a patient with atopic dermatitis: a case report study

, 2019
Sakhar S Albader,1 Abdulmajeed A Alharbi,2 Rakan F Alenezi,1 Fahad M Alsaif31College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2College of Medicine, Alqassim University, Qassim, Saudi Arabia; 3Division of Dermatology, College of Medicine ...
Alharbi AA, Albader SS, Alsaif FM, Alenezi RF   +3 more
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The Utility of Intranasal Corticosteroids in Association With Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: A Real‐Life Multicenter Study by a Tuscany Group

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando, Giuseppe Licci, Marella Reale, Veronica Seccia, Alessia Giorli, Paolo Iannicelli, Dario Zaccari, Valentina Rossi, Jacopo Cambi, Stefano Berrettini, Marco Mandalà, Gianluca Leopardi, Antonio Sarno, Luca Muscatello, Simone Bocuzzi, Franco Trabalzini, Giandomenico Maggiore, Oreste Gallo   +17 more
wiley   +1 more source

Long-term mortality outcomes among immunotherapy recipients treated with dupilumab for the management of cutaneous immune-related adverse events

Journal for ImmunoTherapy of Cancer
Background Dupilumab has been added to National Cancer Comprehensive Network guidelines as a therapeutic strategy for managing certain cutaneous immune-related adverse events (cirAEs) from immune checkpoint blockade (ICB).
Shadmehr Demehri, Kerry L Reynolds, Yevgeniy R Semenov, Matthew Tran, Nicole R LeBoeuf, Suzanne Xu, Guihong Wan, Bonnie W Leung, Emma Beagles, Sara Khattab, Cameron Moseley, Chuck Lin, Marjan Azin, Ninghui Hao   +13 more
doaj   +1 more source

Profile of dupilumab and its potential in the treatment of inadequately controlled moderate-to-severe atopic dermatitis

, 2018
Olabola Awosika,1 Lori Kim,2 Momina Mazhar,2 Monica Rengifo-Pardo,1,2 Alison Ehrlich1,2 1Department of Dermatology, The George Washington Medical Faculty Associates, Washington, DC, USA; 2George Washington University School of Medicine & Health ...
Awosika O, Ehrlich A, Kim L, Rengifo-Pardo M, Mazhar M   +4 more
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Dupilumab: First Global Approval

, 2018
Compliance with Ethical Standards Disclosure: The preparation of this review was not supported by any external funding. During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article ...
Matt Shirley (4977308)
core   +1 more source

Generative AI and Clinicians Show Comparable Prognostic Reasoning From Clinical Narratives in Biologic‐Treated CRSwNP

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To compare the ability of large language models (LLMs) and otolaryngologists to identify prognostic signals from brief clinical vignettes in CRSwNP. Methods In this blinded study, 68 adults initiating biologic therapy for CRSwNP (≥ 36 months follow‐up) were represented by standardized vignettes derived from documentation immediately ...
Sholem Hack, Chase Kahn, Ainhoa Garcia‐Lliberos, Cristina Rodriguez‐Prado, Ameen Biadsee, Maxime Fieux, Mark Liu, Eran Glikson, Masayoshi Takashima, Omar G. Ahmed, Raj Sindwani, Dennis M. Tang, Christopher R. Roxbury   +12 more
wiley   +1 more source

Erythema nodosum followed by eosinophilic pneumonia as an adverse effect of dupilumab treatment in a patient with severe asthma

Respiratory Medicine Case Reports
Dupilumab is a monoclonal antibody that has recently been introduced for the treatment of asthma. It has the potential to significantly alter the progression and severity of T2 -dependent diseases, including severe asthma.
Agnieszka Gawlewicz-Mroczka, Marek Przybyszowski, Grażyna Bochenek, Maria Mroczka, Krzysztof Sładek   +4 more
doaj   +1 more source