Results 181 to 190 of about 121,764 (280)

Time-Resolved Fluorescence Detection of Nicked DNA via Site-Specific Stacking of Sulfo-Cy3: The Role of Charge, Polarity, Linker, and Sequence Context. [PDF]

J Phys Chem B
Berrocal-Martin R, Sansom HG, Orosz K, Paterson MB, Smith BO, Magennis SW.   +5 more
europepmc   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Detection of Certain Berries in Difficult Samples by Singleplex and Multiplex Real-Time PCR-HRM: A Case Study of Pitfalls. [PDF]

Methods Protoc
Fialova L, Marova I.
europepmc   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Self-Avoiding Gamma Peptide Nucleic Acids for Selective Targeting of RNA Secondary Structures. [PDF]

ACS Chem Biol
Dhami I, Thadke SA, Perera JDR, Batwal R, Zheng E, Thrikawala SW, Aryal B, Ly DH.   +7 more
europepmc   +1 more source

The structural basis of differential DNA sequence recognition by restriction–modification controller proteins [PDF]

, 2012
Ball, Neil J., Kneale, Geoff, McGeehan, John, Streeter, Simon, Thresh, Sarah   +4 more
core   +1 more source

Effect of Milling and Wire Electric Discharge Machining on Recast Layer Formation and Tensile Behavior of Metallic Materials

MetalMat, EarlyView.
ABSTRACT Machining of materials is an invaluable technique to give specific shapes and dimensions of desired materials. Different machining processes give rise to different surface characteristics that include not only surface roughness but also specific surface morphology, such as the recast layer.
Animesh Kumar Basak, Alokesh Pramanik, Afifah Zakiyyah Juri, Nachimuthu Radhika, T. Mohanraj   +4 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Two-photon excitation enables single-molecule detection of a fluorescent base analogue in DNA with high photostability. [PDF]

Chem Sci
Sansom HG, Bailie AE, Stefanou F, Purse BW, Jones AC, Magennis SW.   +5 more
europepmc   +1 more source

Proteomic Characterization of AS1411 Reveals ATP6AP1 as a Mediator of Triple‐Negative Breast Cancer Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae, Yun‐Jeong Seo, Eun‐Bi Kim, Hyoung‐Min Park, I‐Hsuan Liu, J. Eugene Lee, Jae‐Young Kim   +6 more
wiley   +1 more source