Results 191 to 200 of about 121,764 (280)

Plasmonic Nano-bolas Hunt DNA Targets. [PDF]

open access: yesACS Nanosci Au
Cencini A   +7 more
europepmc   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

open access: yesPest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden   +3 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

open access: yesPhytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou   +9 more
wiley   +1 more source

2'-Ribose-modified nucleotides: A strategy for reducing off-target effects of oligonucleotide drugs. [PDF]

open access: yesMol Ther Nucleic Acids
Zhang H   +9 more
europepmc   +1 more source

Green Transformational Leadership, GHRM, and Pro‐Environmental Behavior: Pathways to Sustainable Healthcare

open access: yesSustainable Development, EarlyView.
ABSTRACT This study examines the impact of green transformational leadership, green human resource management, and pro‐environmental behavior on sustainable performance. Despite the increasing emphasis on environmental sustainability, the mechanisms through which organizational practices translate into sustainable outcomes remain insufficiently ...
Sharifa Khalid. Mousa   +2 more
wiley   +1 more source

Near‐Atomic Investigation on the Elemental Redistribution During Coprecipitation of Nano‐Sized Kappa‐Type and B2 Precipitates in an Al‐Alloyed Lightweight Steel

open access: yessteel research international, EarlyView.
Elemental redistribution during coprecipitation of kappa (κ)‐type and B2 precipitates in an Al‐alloyed lightweight steel is revealed by atom probe tomography (APT) and density functional theory (DFT). Fe and Ni redistribution promotes the evolution of B2 phase from NiAl‐type toward FeAl‐type and improves the stability of κ and B2 phases during ...
Bowen Zou   +6 more
wiley   +1 more source

A spring-loaded grip-and-pull mechanism for stepwise RNA duplex unwinding by Xrn1. [PDF]

open access: yesNucleic Acids Res
Rhee J   +8 more
europepmc   +1 more source

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