Emerging experimental and bioinformatic approaches in RNA interference‐based pest control research
Double‐stranded RNA (dsRNA) visualization, RNA‐induced silencing complex (RISC)‐bound sRNA‐seq and RNA degradomics allow investigating dsRNA uptake and processing, guide small interfering RNA selection and RISC‐mediated target mRNA cleavages. Transcriptomic and proteomic profiles of genome‐wide responses to dsRNA, including off‐target and compensatory ...
Doga Cedden
wiley +1 more source
A tunable autonomous RNA-fueled micro-engine. [PDF]
Wang K +10 more
europepmc +1 more source
Abstract Methods using environmental nucleic acids have become highly effective for monitoring aquatic biodiversity, with an array of suitable use cases, including metrics for fisheries assessment. Traditional methods for assessing fish populations often rely on invasive techniques with limited spatial and temporal coverage.
Ana Ramón‐Laca +6 more
wiley +1 more source
Synthesis and properties of l-<i>lyxo</i>-thioBsNA-pyrimidine nucleoside: a sulfur-containing analogue of boat-shaped pyranosyl nucleic acid. [PDF]
Ito M +4 more
europepmc +1 more source
Synergistic engineering of Casδ nuclease for robust genome editing
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge +16 more
wiley +1 more source
Interaction of Carbon Dots with Nucleic Acids Is Driven by Their Surface Charge. [PDF]
Nedělníková A +6 more
europepmc +1 more source
The Cost of Convenience: A Hedonic Approach to Travel Time Valuation and Cost‐Benefit Analysis
ABSTRACT This paper presents a novel revealed‐preference approach to estimating the value of travel time (VTT) and calculating consumer surplus for the economic evaluation of transport infrastructure. Departing from traditional stated‐preference models, we derive time valuations by linking residential rental transactions in Greater Sydney to employment
Isaac Mann, David M. Levinson
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The Nuclease Domain of E. coli RecBCD Helicase Regulates DNA Binding and Base Pair Melting. [PDF]
Hao L, Zhang R, Lohman TM.
europepmc +1 more source
The algal homolog of the plant CER1 and CER3 proteins is a bifunctional hydrocarbon‐forming enzyme
Schematic representation of the proposed reactions carried out by a CER1/3 protein from green algae. CoA, coenzyme A; CTD, C‐terminal domain; Cys, catalytic cysteine of C‐terminal domain; His, catalytic histidines of N‐terminal domain; NTD, N‐terminal domain.
Ángel Baca‐Porcel +9 more
wiley +1 more source
Molecular Dynamics Simulation-Assisted siRNA Design for Dual-Ubiquitinated SKP2 Silencing via Ago2 Anchoring in Breast Cancer. [PDF]
Gupta MK, Sudandiradoss C.
europepmc +1 more source

