Results 51 to 60 of about 1,100,479 (387)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Concrete Repair Durability [PDF]

open access: yesMaterials, 2020
The repairs of building structures are inevitable and indispensable. Repairs are used to restore or maintain the usability of existing facilities, often contributing to the extension of their expected service life, increasing the sustainability of building resources.
Lech Czarnecki   +2 more
openaire   +2 more sources

Studies on durability of sustainable biobased composites: a review

open access: yesRSC Advances, 2020
Global concerns over environmental issues have led to a tremendous growth in sustainable materials emerging from biobased plastics and their composites (biocomposites).
B. P. Chang, A. Mohanty, M. Misra
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

The Path to Durable Linearizability

open access: yesProceedings of the ACM on Programming Languages, 2023
There is an increasing body of literature proposing new and efficient persistent versions of concurrent data structures ensuring that a consistent state can be recovered after a power failure or a crash. Their correctness is typically stated in terms of durable linearizability (DL), which requires that ...
Emanuele D'Osualdo   +2 more
openaire   +3 more sources

Na-doped ruthenium perovskite electrocatalysts with improved oxygen evolution activity and durability in acidic media

open access: yesNature Communications, 2019
The design of active and durable catalysts for the H2O/O2 interconversion is one of the major challenges of electrocatalysis for renewable energy. The oxygen evolution reaction (OER) is catalyzed by SrRuO3 with low potentials (ca.
M. Retuerto   +12 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Bond Performance of Carbon Fiber-Reinforced Polymer Bar with Dual Functions of Reinforcement and Cathodic Protection for Reinforced Concrete Structures

open access: yesAdvances in Polymer Technology, 2020
The dual function of a carbon fiber-reinforced polymer (CFRP) bar working as reinforcement and impressed current cathodic protection (ICCP) anode for reinforced concrete structures has been proposed and researched in this paper.
Yingwu Zhou   +5 more
doaj   +1 more source

Tree crown architecture: a tool for decay resistance evaluation [PDF]

open access: yes, 2013
The variability of natural durability contributes to the bad perception of some wood end-users. In our search, we need to adjust our methods and strategies to estimate natural durability and extract higher value from wood resources.
Amissa Adima, Augustin   +5 more
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