Results 91 to 100 of about 32,258 (304)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Forecasting Using Targeted Diffusion Indexes [PDF]

open access: yes
The simplicity of the standard diffusion index model of Stock and Watson has certainly contributed to its success among practitioners resulting in a growing body of literature on factor-augmented forecasts.
António Rua   +2 more
core  

The risk prediction of acute simple bronchitis’ prolonged duration in children

open access: yesZdorovʹe Rebenka, 2019
Background. Factors and mechanisms for the formation of a long course of acute simple bronchitis in children today are unknown finally. The participation of a big number different factors, including clinical, laboratory immunological indicators, is ...
O.O. Ahafonova, N.M. Tokarieva
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

EV with duration forecasting. Case study

open access: yes, 2015
EV with duration forecasting.
Ziółkowska, Aneta
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Comparison of MSACD models

open access: yes, 2005
We propose a new framework for modelling time dependence in duration processes on financial markets. The well known autoregressive conditional duration (ACD) approach introduced by Engle and Russell (1998) will be extended in a way that allows the ...
Hujer, Reinhard   +2 more
core  

Mining the past to forecast the future: comments [PDF]

open access: yes, 2009
In forecasting, data mining is frequently perceived as a distinct technological discipline without immediate relevance to the challenges of time series prediction.
Crone, S
core  

Forecasting the Duration of Political Instabiity

open access: yes, 2012
This paper uses insights from onset-forecasting models constructed by Goldstone (2010) and Fearon (2003) to generate duration models with various hazard rates in the R package Zelig (Imai 2011).
Alexander Sahn, Kevin Huang
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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