Results 111 to 120 of about 32,258 (304)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Machine Learning Models for Spring Discharge Forecasting

Geofluids, 2018
Nowadays, drought phenomena increasingly affect large areas of the globe; therefore, the need for a careful and rational management of water resources is becoming more pressing. Considering that most of the world’s unfrozen freshwater reserves are stored
Francesco Granata, Michele Saroli, Giovanni de Marinis, Rudy Gargano   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

COST ES0602: towards a European network on chemical weather forecasting and information systems [PDF]

Advances in Science and Research, 2009
The COST ES0602 action provides a forum for benchmarking approaches and practices in data exchange and multi-model capabilities for chemical weather forecasting and near real-time information services in Europe.
J. Kukkonen, T. Klein, K. Karatzas, K. Torseth, A. Fahre Vik, R. San José, T. Balk, M. Sofiev   +7 more
doaj  

COVID-19 Pandemic: Duration and Epidemiological Forecast

Problems of Particularly Dangerous Infections
The World Health Organization declared COVID-19 a pandemic on March 11, 2020. While in March 2022, i.e. approximately two years later, the global dominance of the phylogenetic variant of SARS-CoV-2 Omicron with its associated milder clinical course of the disease was registered, and therefore an epidemiological forecast was made about the onset of a ...
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Duration-Dependent Regime Switching Model for an Open Emerging Economy [PDF]

We employ duration-dependent Markov-switching vector auto-regression (DDMSVAR) methodology to construct an economic cycle model for an emerging economy.
Ozun, Alper, Turk, Mehmet
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Physical Mechanisms of Clear Air Turbulence

East European Journal of Physics
Clear air turbulence (CAT) is a significant type of atmospheric turbulence that poses risks to aviation. Unlike other forms of turbulence, it occurs without substantial cloudiness, often under clear skies or with minimal cloud cover at the observation ...
V.O. Lykhatskyi, V.I. Tkachenko, L.S. Bozbiei   +2 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source