Results 81 to 90 of about 168,322,127 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Determinants of Unemployment Duration in Russia [PDF]
Using information contained in a nationally representative, longitudinal survey of Russian citizens, this research analyzes the determinants of unemployment duration during the early stages of economic transition. A competing-risks, discrete-time waiting
Mark C. Foley
core
Unemployment duration among immigrants and natives: unobserved heterogeneity in a multi-spell duration model [PDF]
, 2008 This paper studies whether the unemployment dynamics of immigrants differ from those of natives, paying special attention to the impact of accounting for unobserved heterogeneity among individuals.
García Pérez, J. Ignacio +1 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Other title: Federal self assessment report
, 2013 Annual; Oct. 1, 2002 through Sept. 30, 2003-; Title from cover.; Vols. for 2003/04- also called 7th-; Issued in cooperation with the Connecticut Judicial Branch's Support Enforcement Services ...
Connecticut Child Support Program.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Adolescent bereavement and social support perception of need according to gender [PDF]
, 2001 Plan BIn the empirical studies that have specifically addressed adolescent grief recovery, the issue of gender differences in perceptions of social support following bereavement has not been thoroughly examined. The purpose of this study was to determine
Katzenmeyer, Lynn M.
core
BMC GeriatricsBackground Previous research has overlooked the complex interactions of factors influencing sarcopenia risk. Therefore, this study aimed to identify prevalence and factors associated with sarcopenia risk in older adults with diabetes and to determine ...
Ni Sang +7 more
doaj +1 more source
Facebook Use and Well-Being Among Army Veterans With PTSD
International Journal of Communication, 2021 This study examines the connection between the duration of Facebook use and psychological well-being among army veterans with posttraumatic stress disorder (PTSD).
Daphna Yeshua-Katz, Tanya Zilberstein
doaj