Results 101 to 110 of about 168,322,127 (297)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Feb.
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Background The population of African migrant women in the United States (U.S.) is steadily increasing, yet limited research exists on their breastfeeding experiences, support systems, and sources of breastfeeding information.
Tabitha Addy +5 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Electronic coverage as of Oct. 23, 2009: 1998-; In July 2000, Office moved from Ohio Dept. of Human Services to Ohio Dept. of Job and Family Services.; Title from caption of index screen (viewed Nov.
Ohio. Office of Child Support.
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
PREDICTING CONSTRUCTION PROJECT DURATION WITH SUPPORT VECTOR MACHINE
This paper presents a forecasting model for constru ction time, using support vector machine (SVM) ‐ re cently one of the most accurate predictive models. Every construction contract contains project deadli ne as an essential element of the contract. The pra ctice shows that a considerably present problem is that of non-compliance of the co ntracted ...
openaire +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Background: The health benefits of exclusive breastfeeding (EBF) are well established; however, adherence to recommended durations remains suboptimal.
Zhili Chen, Haihua Lin, Yanfen Liao
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

