Results 91 to 100 of about 168,322,127 (297)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The duration derby: a comparison of duration based strategies in asset liability management [PDF]

open access: yes, 2001
Macaulay duration matched strategy is a key tool in bond portfolio immunization. It is well known that if term structures are not at or changes are not parallel, then Macaulay duration matched portfolio can not guarantee adequate immunization.
Allen, David E.   +2 more
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The importance of word-final vowel duration for non-native portuguese speaker identification by means of Support Vector Machines

open access: yesRevista Brasileira de Linguística Aplicada, 2014
This article studies the acoustic characteristics of some oral vowels in tonic syllables of Brazilian Portuguese (BP) and which acoustic features are important for classifying native versus non-native speakers of BP.
Suzanne Franks, Rommel Barbosa
doaj  

Factors relating with exercise duration of phase I cardiac rehabilitation for patients after percutaneous coronary intervention

open access: yesZhongguo kangfu lilun yu shijian
Objective To investigate the current status of exercise duration of phase I cardiac rehabilitation for patients after percutaneous coronary intervention (PCI), and analyze its related factors.
XUE Lei
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Social anxiety among young adults in Switzerland: a cross-sectional study on associations with sports and social support

open access: yesBMC Psychology
Background This cross-sectional study examined the relationship of sports and perceived social support with social anxiety in young adults. We aimed to find out whether participation in sports and good social support were associated with lower social ...
Irma Heller   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Caregiver Burden in Chronic Diseases: Role of Perceived Social Support and Duration of Care in Arthritis and Diabetes

open access: yesPakistan Armed Forces Medical Journal
Objective: To assess the relationship between caregiver burden and perceived social support, and caregiver burden and caregiving duration of arthritis and diabetes, and to analyze gender differences.
Maryam Umar   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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