Results 91 to 100 of about 168,322,127 (297)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The duration derby: a comparison of duration based strategies in asset liability management [PDF]
Macaulay duration matched strategy is a key tool in bond portfolio immunization. It is well known that if term structures are not at or changes are not parallel, then Macaulay duration matched portfolio can not guarantee adequate immunization.
Allen, David E. +2 more
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
This article studies the acoustic characteristics of some oral vowels in tonic syllables of Brazilian Portuguese (BP) and which acoustic features are important for classifying native versus non-native speakers of BP.
Suzanne Franks, Rommel Barbosa
doaj
Objective To investigate the current status of exercise duration of phase I cardiac rehabilitation for patients after percutaneous coronary intervention (PCI), and analyze its related factors.
XUE Lei
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Background This cross-sectional study examined the relationship of sports and perceived social support with social anxiety in young adults. We aimed to find out whether participation in sports and good social support were associated with lower social ...
Irma Heller +5 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Objective: To assess the relationship between caregiver burden and perceived social support, and caregiver burden and caregiving duration of arthritis and diabetes, and to analyze gender differences.
Maryam Umar +2 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

