Results 101 to 110 of about 36,256 (261)

Terapia del carcinoma de células renales [PDF]

, 2018
El cáncer renal se encuentra entre los 10 tipos de cánceres más diagnosticados a nivel mundial, representando entre el 3-5% de todos los casos diagnosticados. Una detección precoz suele estar asociada con un pronóstico favorable.
Ramírez Sánchez, Pablo
core  

Efficacy and Safety of Second‐Line Lenvatinib After First‐Line Durvalumab Plus Tremelimumab in Unresectable Hepatocellular Carcinoma

Hepatology Research, EarlyView.
ABSTRACT Background There is a paucity of data regarding the efficacy and safety of lenvatinib as a second‐line treatment following first‐line combination immunotherapy with durvalumab and tremelimumab (Dur + Tre). Methods This retrospective multicenter study included 14 patients with unresectable hepatocellular carcinoma who received lenvatinib after ...
Ryoichi Miura, Tomokazu Kawaoka, Saki Sueda, Aiko Tanaka, Kou Hashimoto, Tomoaki Emori, Yasutoshi Fujii, Hatsue Fujino, Atsushi Ono, Eisuke Murakami, Daiki Miki, Shinsuke Uchikawa, Nami Mori, Keiji Tsuji, Yosuke Suehiro, Keiichi Masaki, Michihiro Nonaka, Kenji Yamaoka, Yoshio Katamura, C. Nelson Hayes, Masataka Tsuge, Shiro Oka   +21 more
wiley   +1 more source

Real-world prospective analysis of treatment patterns in durvalumab maintenance after chemoradiotherapy in unresectable, locally advanced NSCLC patients [PDF]

, 2021
Julian Taugner, Lukas Käsmann, Chukwuka Eze, Alexander Rühle, Amanda Tufman, Niels Reinmuth, Thomas Duell, Claus Belka, Farkhad Manapov   +8 more
openalex   +1 more source

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

Histopathology, EarlyView.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda, Roberto Salgado, Filip van Herpe, Daniel Sur, Michael Vieth, Sherene Loi, Ahmad P Tafti, Hardas Alexandros, Akira I Hida, Amarpreet Bhalla, Andrey I Khramtsov, Anna Ehinger, Atsushi Tanaka, Balazs Acs, Caner Ercan, Cornelia M Focke, Daniel Ehinger, Dan Huang, Galina F Khramtsova, Haruto Nishida, Nianyi Li, Nickolas Littlefield, Sanna Steen, Selim Sevim, Shin Ichihara, Shinnosuke Morikawa, Stefan Michiels, Thomas Papathomas, Toshihiro Haga, Qiangqiang Gu, Weiqi Sheng, Hoel Kervadec, Hugo M Horlings, Francisco Sanchez‐Vega, Yelena Y Janjigian, Myriam Chalabi, Hanneke W M van Laarhoven, Liudmila L Kodach, Sybren L Meijer   +38 more
wiley   +1 more source

Durvalumab-associated limbal stem cell deficiency and secondary corneal perforation

American Journal of Ophthalmology Case Reports
Purpose: We report a patient with bilateral limbal stem cell deficiency (LSCD) like clinical manifestations and secondary corneal perforation presumably induced by durvalumab following its use for the treatment of non-small cell lung carcinoma ...
Nahrain Putris Schumaier, David G. Heidemann, Chirag Gupta   +2 more
doaj   +1 more source

Cutaneous Immune‐Related Adverse Events and Efficacy of Immune Checkpoint Inhibitors for Patients With Advanced Solid Organ Malignancies

International Journal of Dermatology, EarlyView.
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for patients with advanced solid tumors. While low‐grade immune‐related adverse events (irAEs) are associated with prolonged survival, high‐grade irAEs have been associated with poorer survival. Cutaneous immune‐related adverse events (cirAEs) affect up to 20%
David O'Reilly, Gregg Murray, Orla M Fitzpatrick, Hebatalla Ismail, Gavin P Dowling, Gargi Roy, David Synnott, Maggie O'Connor, Bryan T Hennessy, Oscar Breathnach, Liam Grogan, Megan Greally, Adrian Murphy, Patrick G Morris, Karen Eustace, Muireann Roche, Stephen Madden, Jarushka Naidoo   +17 more
wiley   +1 more source

Machine learning modeling of patient health signals informs long-term survival on immune checkpoint inhibitor therapy

iScience
Summary: System-level patient health signals, as captured by treatment-emergent adverse events (TEAEs), might contain correlates of immune checkpoint inhibitor (ICI) therapy response.
Gerald J. Sun, Gustavo Arango-Argoty, Gary J. Doherty, Damian E. Bikiel, Dejan Pavlovic, Allen C. Chen, Ross A. Stewart, Zhongwu Lai, Etai Jacob   +8 more
doaj   +1 more source

Prognostic and Predictive Role of PD-L1 Expression in Stage III Non-small Cell Lung Cancer Treated With Definitive Chemoradiation and Adjuvant Durvalumab

, 2022
Alex K. Bryant, K. Nathan Sankar, Garth W. Strohbehn, Lili Zhao, Victoria Daniel, David J. Elliott, Nithya Ramnath, Michael D. Green   +7 more
openalex   +2 more sources

Scheduled Inside Plastic Stent Exchange Prevents Cholangitis and Reduces Unplanned Hospitalization in Patients With Unresectable Malignant Hilar Biliary Obstruction

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives To prevent cholangitis in patients with unresectable malignant hilar biliary obstruction (MHBO), we recently implemented scheduled inside plastic stent (IS) exchange every 2–4 months. This study aimed to evaluate whether this strategy prevents cholangitis onset and reduces unplanned hospitalizations without increasing adverse events.
Joji Muramatsu, Kazuma Ishikawa, Norito Suzuki, Tomohiro Kubo, Makoto Yoshida, Ginji Omori, Ryo Ito, Shogo Miura, Kohichi Takada   +8 more
wiley   +1 more source

Novel Closure Technique With Double‐Balloon Endoscopy‐Guided Embolization by Gelatin Sponge and Clip Suturing for Postoperative Enterocutaneous Fistula With Bile Leakage

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 60‐year‐old female with abdominal pain and nausea was diagnosed with gallbladder cancer (cT3aN2M1, cStage IVB). Distant metastases had disappeared after 10 courses of chemotherapy, followed by conversion surgery consisting of subtotal stomach‐preserving pancreaticoduodenectomy, partial hepatectomy, and dissection of para‐aortic and regional ...
Yuki Ito, Hiroshi Yukimoto, Kohsaku Ohnishi, Takafumi Tanimoto, Motohiro Hirao, Yasuhiro Nakaya, Daisuke Takiuchi, Masanori Tsujie, Atsushi Hosui, Naoki Hiramatsu   +9 more
wiley   +1 more source