Results 31 to 40 of about 295,856 (309)

A Study on Dust-Control Technology Used for Large Mining Heights Based on the Optimization Design of a Tracking Spray Nozzle

open access: yesAtmosphere, 2023
Intense cutting-induced dust production in fully mechanized mining faces (FMMFs) with large mining heights produces a high amount of dust that is difficult to capture and severely affects the working environment, threatening the health of occupational ...
Zuxiang Hu, Benyi Zhang, Haoqian Chang
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

A combination of PD-1 and TIGIT immune checkpoint inhibitors elicits a strong anti-tumour response in mesothelioma

open access: yesJournal of Experimental & Clinical Cancer Research
Background Finding effective and curative treatment for mesothelioma remains challenging. While the introduction of immunotherapy combinations using ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) have offered hope for some patients, a large ...
Huaikai Shi   +17 more
doaj   +1 more source

Management from the Perspective of Islam [PDF]

open access: yesپژوهش نامه معارف قرآنی, 2011
Islamic management is one of the necessities of an Islamic society. Therefore, any Islamic society requires a management system which is in line with Islamic patterns and is at the service of the Islamic society.
abbas azizi mehman dust, saeed sehat
doaj   +1 more source

Basic characteristics of mine dust suppression foam and the quantitative evaluation method of its performance

open access: yesMeitan xuebao, 2023
The priority direction of mine dust control is to suppress dust generation and flying at the source. Foam, a gas-liquid two-phase medium, has some unique advantages of large dust covering area, strong adhesion ability and fast wetting of dust.
Hetang WANG   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Behavior and hippocampal Epac signaling to nicotine CPP in mice

open access: yesTranslational Neuroscience, 2019
Tobacco use is a major challenge to public health in the United States and across the world. Many studies have demonstrated that adult men and women differ in their responses to tobacco smoking, however neurobiological studies about the effect of smoking
Liu Jing   +7 more
doaj   +1 more source

Analysis of gamma-emitting radionuclides in soils around high energy accelerators

open access: yesRadiation Medicine and Protection, 2022
Objective: To investigate the specific activities of gamma radionuclides in the soils around high energy accelerators, and to analyze the influence of rays emitted by nuclides with characteristic peaks at similar energy points on nuclide measurement ...
Jiaying Wang   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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