Results 81 to 90 of about 334,620 (310)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Solar radiative effects of non-spherical mineral dust particles during SAMUM 2006 [PDF]

, 2008
During the SAMUM campaign comprehensive measurements were performed in May-June 2006 concerning the physico-chemical and radiative properties of Saharan mineral dust.
Weinzierl, Bernadett, Otto, Sebastian, Tesche, Matthias, Bierwirth, Eike, Esselborn, Michael, Kandler, Konrad, Trautmann, Thomas, Wendisch, Manfred   +7 more
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Application of a transient hygrothermal population model for house dust mites in beds: assessment of control strategies in UK buildings [PDF]

, 2011
This article discusses the capabilities and the application of an innovative combined hygrothermal and population model to assess the impact of building design and occupant behaviour on house dust mite populations in a mattress. The combined model is the
Crowther, David, Biddulph, Philip, Biddulph, P, Phillip Biddulph, Toby Wilkinson, Barbara Hart, Tadj Oreszczyn, Oreszczyn, Tadj, Ridley, Ian, Ridley, I, Crowther, D, Oreszczyn, T, Pretlove, S, Hart, B, Ian Ridley, Wilkinson, T, Hart, Barbara, Marcella Ucci, Ucci, Marcella, Pretlove, Stephen E. C., David Crowther, Wilkinson, Toby, Stephen E. C. Pretlove, UCCI, M   +23 more
core   +1 more source

Research and Innovation on House Dust Mites

Siriraj Medical Journal, 2020
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Vanna Mahakittikun, John J. Boitano
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A Study on Dust Dry Deposition: Wind-tunnel Experiment and Improved Parameterization [PDF]

, 2013
Dust deposition is a key component of the dust cycle in the Earth system. The lack of understanding for the mechanisms of dust deposition has been a major bottle neck to the development of the dust-related research field.
Zhang, Jie
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

[Concert Poster: Dust Congress] [PDF]

, 2007
Poster/flyer advertising a concert by Dust Congress, Glossary and Sarah Reddington on April 29, 2007, at Hailey's Club in Denton, TX. Poster shows a hand drawn line drawing of a beached whale and lists titles of Dust Congress songs: Midnight @ the ...

core  

Experimental study of the role of physicochemical surface processing on the IN ability of mineral dust particles [PDF]

, 2011
During the measurement campaign FROST 2 (FReezing Of duST 2), the Leipzig Aerosol Cloud Interaction Simulator (LACIS) was used to investigate the influences of various surface modifications on the immersion freezing behavior of Arizona Test Dust (ATD ...
A. Kiselev, T. Clauss, Buchholz, A., E. Mikhailov, Stetzer, O., Kiselev, A., Sullivan, Ryan; id_orcid, Shaw, R. A., Bundke, Ulrich, P. J. DeMott, Reimann, Bernd, Mentel, T. F., Kiselev, Alexei, Wex, Heike, Stratmann, Frank, DeMott, P.J., Reitz, P., S. Hartmann, Clauss, T., B. Reimann, Petters, M., Reimann, B., O. Stetzer, P. Reitz, U. Bundke, Sullivan, R., Hartmann, Susan, Mentel, Thomas F., Sierau, Berko, Mikhailov, E., Petters, Markus D., Shaw, R.A., Stetzer, Olaf, DeMott, Paul J., R. C. Sullivan, Shaw, R., DeMott, P., Niedermeier, Dennis, Petters, M.D., R. A. Shaw, Bundke, U., A. Buchholz, Reitz, Paul, F. Stratmann, DeMott, P. J., Hartmann, S., J. Schneider, Petters, M. D., Schneider, Johannes, Wex, H., Shaw, Raymond A., H. Wex, Niedermeier, D., Sullivan, Ryan C., Stratmann, F., Sullivan, R.C., Sullivan, R. C., Mentel, T.F., Schneider, J., B. Sierau, Clauss, Tina, Buchholz, Angela, D. Niedermeier, M. D. Petters, Mentel, T., T. F. Mentel, Mikhailov, Eugene, Sierau, B.   +67 more
core   +1 more source