Results 71 to 80 of about 334,620 (310)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Dust [PDF]

, 2015
Dust is envisioned as a contemporary performance investigation of a future apocalyptic world. Set in a climate changed wasteland of our own making, Dust explores the days after the day of the cataclysmic natural disaster that heralded the end of the ...
Linda Hassall (13212156)
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Experimental and numerical simulation study on forced ventilation and dust removal of coal mine heading surface

International Journal of Coal Science & Technology
In order to study the problems of unreasonable airflow distribution and serious dust pollution in a heading surface, an experimental platform for forced ventilation and dust removal was built based on the similar principles.
Haotian Zheng, Bingyou Jiang, Haoyu Wang, Yuannan Zheng   +3 more
doaj   +1 more source

Prediction of heterogeneous nucleation condensation effect on the surface of respiratory coal dust and test of dust reduction test

Meitan xuebao
Surface wettability of coal dust particles is an important factor restricting the efficiency of wet dust removal. Heterogeneous nucleation condensation on the surface of coal dust particles is a means without any pollution, without considering the ...
Hanyi LIN, Liang YUAN, Bingyou JIANG, Yuqian ZHANG, Yifan WANG, Haoyu WANG   +5 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Characterization of explosion propagation of coal dust deposited by gas explosion convolutions in closed pipelines

Meitan xuebao
To explore the propagation characteristics of gas explosion-induced coal dust detonations in enclosed pipelines, a custom-developed experimental system was employed for gas explosions involving accumulated coal dust.
Bingyou JIANG, Han HONG, Mingqing SU, Kunlun LU, Binghui YANG, Peilong WANG, Dawei DING   +6 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Diversity in the outcome of dust radial drift in protoplanetary discs [PDF]

, 2014
C. Pinte acknowledges funding from the European Commission’s FP7 (contract PERG06-GA-2009-256513) and the Agence Nationale pour la Recherche of France (contract ANR-2010-JCJC-0504-01). G.
C. Pinte, Pinte, C., G. Laibe, Laibe, G.
core   +1 more source