Results 71 to 80 of about 10,339 (261)

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

Advanced Healthcare Materials, EarlyView.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng, Pei‐Wei Weng, Hsien‐Tsung Lu, Jiunn‐Horng Kang, Lekha Rethi, Lekshmi Rethi, Yan‐Ting Chen, Hieu Trung Nguyen, Yao‐Tung Tsai, Andrew E.‐Y. Chuang   +9 more
wiley   +1 more source

Modeling global surface dust deposition using physics-informed neural networks

Communications Earth & Environment
Paleoclimatic measurements serve to understand Earth System processes and evaluate climate model performances. However, their spatial coverage is generally sparse and unevenly distributed across the globe.
Constanza A. Molina Catricheo, Fabrice Lambert, Julien Salomon, Elwin van ’t Wout   +3 more
doaj   +1 more source

The Physical Basis for the Silicate Dust Sequence

The Astrophysical Journal, 2001
Using a series of radiative transfer models of circumstellar dust shells, we explore the physical origins of the variety of shapes of the 10 μm silicate feature seen in the spectra of oxygen-rich circumstellar dust shells. In order to match the full range of observed spectral shapes, the models explore four parameters: the relative abundance of ...
M. P. Egan, G. C. Sloan
openaire   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source

Zero-Shot Sand-Dust Image Restoration

Sensors
Natural sand-dust weather is complicated, and synthetic sand-dust datasets cannot accurately reflect the properties of real sand-dust images. Sand-dust image enhancement and restoration methods that are based on enhancement, on priors, or on data-driven ...
Fei Shi, Zhenhong Jia, Yanyun Zhou
doaj   +1 more source

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Perubahan Gambaran Histopatologi Paru pada Paparan Debu Batubara Memakai Alat Model 2010

Majalah Kedokteran Bandung, 2011
Coal mining on surface ground stimulate to create coal dust exposure equipment on laboratory scale. Optimation of model 2010 coal dust exposure equipment focus on coal dust accumulation and histopathologic of lung.
Nia Kania, Bambang Setiawan, Nurdiana Nurdiana, M. Aris Widodo, HMS Chandra Kusuma   +4 more
doaj   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Size Distribution of Small Grains in the Inner Zodiacal Cloud

The Planetary Science Journal
The Parker Solar Probe (PSP) spacecraft has transited the innermost regions of the zodiacal cloud and detects impacts to the spacecraft body via its electric field instrument.
J. R. Szalay, P. Pokorný, D. M. Malaspina   +2 more
doaj   +1 more source