Attitudes of family medicine physicians toward the Turkish-validated 12-item attitude scale for the clinical nutrition care process: a national cross-sectional analysis. [PDF]
Köksal M, Köksal NG, Sengul I.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Cognitive complaints and their associations with role functioning limitations among adolescent and young adult cancer survivors in Hong Kong. [PDF]
Xiao P +9 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Factors affecting task shifting/sharing from physicians to pharmacists in cancer chemotherapy in Japan: A qualitative study. [PDF]
Ikuta K +8 more
europepmc +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Biobanks as fiduciaries of biosamples and data: a legal and ethical analysis in the light of international standards. [PDF]
Tsuruyama T, Hiratsuka T.
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Nationwide trend analysis of burnout among resident physicians in Japan before and after the national workstyle reform: a repeated cross-sectional survey of 25 368 participants. [PDF]
Ono R +7 more
europepmc +1 more source

