Results 131 to 140 of about 1,712,755 (309)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Study on decisionmaking ability and influencing factors of clinical nursing teachers’nursing ethics
Huli yanjiu, 2017 Objective:To probe into the status quo and influencing factors of ethical decisionmaking ability of teachers in clinical nursing teaching.Methods:The whole group selected 84 nursing teachers in 10 hospitals in Wuxi city were selected to teach teachers ...
朱磊, 牛倩, 徐森
doaj
Oversight Commission on Presidential Capacity Act [PDF]
, 2017 A prooposed bill to establish an Oversight Commission on Presidential Capacity in the legislative branch. This commission would be used to determine whether the President is mentally or physically unable to discharge the powers and duties of office.https:
United States. House of Representatives
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
THE PROBATIONARY PERIOD FOR A FIXED-TERM EMPLOYMENT CONTRACT
Вестник университета, 2019 In the article the peculiarities of concluding a fixed term employment contract when hiring employees whose job is temporary, seasonal. Therefore, the analysis of the duration of the probationary period, noted some categories of people having the right ...
T. Suvalova
doaj
The Strategies of Sekar Jagad Pub and Karaoke to Improve The Number of Guests [PDF]
, 2010 Hotel is one of the important elements in tourism industry. A hotel has many departments for its operational activities, one of them is Food and Beverage Department.
Sekaringtyas, Arum
core
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Fiduciary Duties and Equity-Debtholder Conflicts [PDF]
We use an important legal event as a natural experiment to examine the effect of management fiduciary duties on equity-debt conflicts. A 1991 Delaware bankruptcy ruling changed the nature of corporate directors' fiduciary duties in firms incorporated in ...
Bo Becker, Per Strömberg
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source