Results 71 to 80 of about 1,712,755 (309)

The Jurisprudential Turn in Legal Ethics [PDF]

, 2011
When legal ethics developed as an academic discipline in the mid-1970s, its theoretical roots were in moral philosophy. The early theorists in legal ethics were moral philosophers by training, and they explored legal ethics as a branch of moral ...
Kruse, Katherine R.
core   +2 more sources

Obligations in the Shade: The Application of Fiduciary Directors’ Duties to Shadow Directors [PDF]

, 2016
This paper argues that shadow directors, as defined in English law, ought to owe the full range of directors’ duties, both fiduciary and non-fiduciary, enacted in the Companies Act 2006 (CA 2006), ss 171-177, to the relevant company under their influence.
Alexander, Birks, Birks, Birks, Bratton, Brudney, Burrows, Colin R. Moore, Conaglen, Conaglen, Cooter, Davies, DeMott, Edelman, Finn, Finn, Finn, Finn, FitzGibbon, Flannigan, Flannigan, Flannigan, Forrest, Frankel, Galoob, Glover, Glover, Harding, Hoyano, Kershaw, Levi, MacCormick, McCamus, McGhee, Mitchell, Parkinson, Posner, Postema, Prentice, Raz, Rotman, Rotman, Royce, Shepherd, Simmonds, Smith, Summers, Weinrib, Zipursky   +48 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Analysis of Local Taxes in the European Union [PDF]

Ovidius University Annals: Economic Sciences Series, 2016
The fiscal system can be used as a tool for economic life regulation, for the state interventionin the economy in order to eliminate the imbalances in different periods of economic life.
Oana Oprisan, Cosmin Tileagă, Claudiu Valentin Niţu   +2 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Responsibility due to the non-accomplishment of contract duties
A responsabilidade decorrente do inadimplemento dos deveres anexos do contrato

Scientia Iuris, 2009
Contracts are the main instrument of circulation of wealth as well as of the most diverse interests. The problem arises if it does not achieve its purposes and frustrate the interests of those involved, who may decide for the breach of the duty, the core
Cláudio José Franzolin
doaj  

Principle for Effective Insolvence

Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
Insolvency proceedings are complex because they combine 3 components: economic, judicial and social. Consequently, the conduct of these proceedings requires the participation of implementing authorities with a view to achieving the aim laid down by the ...
Anca Roxana Bularca
doaj   +1 more source

THE CORRELATION BETWEEN THE INHERITED DEBT AND THE RIGHT OF OPTION ON SUCCESSION [PDF]

Challenges of the Knowledge Society, 2015
A natural person’s patrimony consists, apart from rights (assets of the succession), of a liabilities side as well related to obligations that the patrimony’s holder bequeaths onto the heirs following his/her death.
Ana-Maria GHERGHINA (VASILE)
doaj