Results 81 to 90 of about 1,712,755 (309)
Buffalo City Comptroller [PDF]
, 2009 Under the Buffalo Charter and Code, the Comptroller is the head of the Department of Audit and Control. The Department of Audit and Control is broken down into three divisions: Division of Audit, Division of Accounting, and Division of Investment and ...
Sparks, Robert
core +1 more source
, 2006 This paper examines whether and how reforms in corporate governance structures and practices in the United States may reshape conventional notions of the fiduciary duties owed by independent directors of public companies.
Akusjärvi, Göran +3 more
core +5 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Lingue e Linguaggi, 2016 – The relation between language and law is very complex and profound, and it includes the ‘intrinsic’ aspect and the ‘extrinsic’ one. The first deals with the theory of juridical interpretation, which is the clearest example of contact between the ...
Giovanni Poggeschi
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
[es] Los fundamentos normativos de las profesiones y los deberes de los trabajadores sociales
Global Social Work, 2010 En este artículo presento un esbozo de estructura de los valores del trabajo social que hagan posible una justificación racional de sus deberes y responsabilidades.
Damián Salcedo Megales
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
, 1996 This law defines the rights, powers, privileges, duties and liabilities of the parties to a ...
Seidman, Ann, Seidman, Robert B.
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source