Results 81 to 90 of about 2,096,377 (330)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

INFLUENCE OF CUSTOMS PAYMENTS ON THE ECONOMIC SECURITY OF THE COUNTRY, PROBLEMS AND WAYS OF OVERCOMING

open access: yesBaltic Journal of Economic Studies, 2017
The article considers the role of customs payments as one of the main revenue sources of the state budget of Ukraine. The volume of receipt of customs payments to the state budget is characterized. The structure of receipts from customs payments for 2016-
Inna Kiyanchuk
doaj  

Jordan Imports and Tariff Regimes: A Revisit [PDF]

open access: yes, 2019
Jordan made substantial market access commitments as part of its WTO membership negotiations. Jordan has low average tariffs with single or two digits rate and ad valorem-only duties with some exceptions where specific duties apply.
Malkawi, Bashar H.
core   +1 more source

Recalcitrant pluralism [PDF]

open access: yes, 2011
Here I argue that the best form of deontology is an ethic of prima facie duties, and that this form of deontology is especially resistant to any form of reduction to a single ...
Stratton-Lake, Philip
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Aristotle on the Normative Value of Friendship Duties [PDF]

open access: yes, 2018
In this article, I present an interpretation of Aristotle’s thought regarding the normative value of friendship duties.The argument is divided in VII sections.
Nascimento, Daniel Simão
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Securities Regulation: Shareholder Derivative Actions Against Insiders Under Rule 10b-5 [PDF]

open access: yes, 1966
After a general examination of Rule 10b-5 in the context of its traditional application, this comment focuses on the recent developments concerning the rule\u27s function as a weapon for the enforcement of controlling insiders\u27 duties to their ...
Caidahl, Kenneth   +4 more
core   +3 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

TAXATION PECULIARITIES OF E-COMMERCE MARKET PLAYERS

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2016
The article carried out with complex overview of tax regulation approaches of e-Commerce market, the features of international practices of taxation are revealed, in particular, EU countries, USA, China, etc.
Т. Zatonatska, О. Melnychuk
doaj   +1 more source

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