Results 91 to 100 of about 149,950 (298)
Duty of care applied to tailings operations
, 2011 The ever increasing costs and risks associated with tailings facilities worldwide have led to the adoption of a Duty of Care in ensuring high standards of tailings operation.
Boswell, Jeremy, Sobkowicz, John
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2014 What is the duty of care and to whom do you, as a health care professional, owe it? Further, to what standard will your duty be held? These are the questions that this article will address.
Cornock, Marc
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Towards a Duty of Care for Biodiversity [PDF]
, 2020 The decline in biodiversity is a worldwide phenomenon, with current rates of species extinction more dramatic than any previously recorded. Habitat loss has been identified as the major cause of biodiversity decline.
C Allan, A Curtis, G Earl
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 2008 The Supreme Court of Canada, by majority, has found a tort of negligent investigation. The reasons for the decision were that there was a sufficiently close relationship between the investigating police officer and the particularized suspect for there to
Yule, Jennifer M.
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Video Sharing Sites’ Fault Identification in Indirect Copyright Infringements
Contemporary Social Sciences, 2019 Under the guidance of "technical value theory" taking both the natural and social attributes of technique into consideration, the fault in indirect infringements of copyrights by video sharing websites includes two forms: "intention" and "negligence". As
Ma Yide
doaj +1 more source
The Duty to Care is Not Dead Yet. [PDF]
Asian Bioeth Rev, 2023 Cong Y, Dwyer J.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source