Results 81 to 90 of about 149,950 (298)

A case study of asthma care in school age children using nurse-coordinated multidisciplinary collaborative practices [PDF]

open access: yes, 2015
Aim: To describe the role of school nursing in leading and coordinating a multidisciplinary networked system of support for children with asthma, and to analyze the strengths and challenges of undertaking and supporting multiagency interprofessional ...
Procter S   +19 more
core   +1 more source

Duty of care on the part of the delegating natural person in the context of functional proxy in environmental matters Hints on Criminal Court of Cassation, sec. III, May 27, 2020 (hearing of February 12, 2020), No. 15941 (Pres. Izzo, Rel. Reynaud) [PDF]

open access: yesLexambiente, 2020
The Third Chamber, with regards to waste disposal issues, reaffirms the case law according to which there is a duty of “high” care on the part of the delegating natural person.
Carlo Melzi D'Eril   +1 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Schools duty of care

open access: yes, 2023
Nadzorstvena dolžnost šole je ena pomembnejših dolžnosti, ki se nalagajo šolam in učiteljem. Kljub temu pa je naša zakonodaja ne definira, zato se je moral pojem natančneje oblikovati skozi sodno prakso.
Kokot, Urška
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Duty of care for mental harm suffered by rescuers

open access: yes, 2010
In Wicks v State Rail Authority NSW; Sheehan v State Rail Authority NSW [2010] HCA 22 (16 June 2010) the duty of care owed to rescuers, who were police officers, at a train derailment, was considered in conjunction with the interpretation of the Civil ...
Yule, Jennifer M.
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

The novel concept of creating awareness about tuberculosis at the metro stations

open access: yesThe Pan African Medical Journal, 2016
Tuberculosis is an infectious disease and is a major health problem in developing countries like India. The disease is prevalent mainly in the underprivileged sections of the society.
Sankalp Yadav, Gautam Rawal
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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