Results 101 to 110 of about 149,950 (298)
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
A lawyer's duty of care : beware the failure to advise of contingencies and foreseeable risks
, 2012 It is trite law that a lawyer owes their client a duty of care requiring the lawyer to take reasonable steps to avoid their client suffering foreseeable economiic loss: Hawkins v Clayton.
Christensen, Sharon A.
core
Duty of care in companion dog owners: Preliminary scale development and empirical exploration. [PDF]
PLoS One, 2023 Glanville CR +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Mortgagees' Duty of Care in Singapore: Staying the Course
, 2009 Whilst mortgagees do not owe mortgagors any general duty of care, they may come under specific duties of care, such as the duty to take reasonable steps to obtain the market price when they exercise their power of sale.
Loi, KCF
core
Ethical Issues in the Dynamic Environment for Public-Stewardship Statistical Information
Data Science in ScienceThis paper explores some ethical issues encountered by managers and others in statistical and data science organizations. It does not spell out detailed ethical requirements.
John L. Eltinge
doaj +1 more source
Nurses' duty to care during the COVID-19 pandemic: a cross-sectional survey. [PDF]
BMC Nurs, 2022 Shin H, Kim KH, Kim JS, Kwak YH.
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Facilitating genetic testing after death: the ongoing duty of care to the deceased and their relatives. [PDF]
J R Soc Med, 2023 Dennis C, Van Dijk FS, Lucassen A.
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source